COVID-19 in patients with HIV-1 infection: a single-centre experience in northern Italy

被引:33
作者
Calza, Leonardo [1 ]
Bon, Isabella [2 ]
Tadolini, Marina [1 ]
Borderi, Marco [1 ]
Colangeli, Vincenzo [1 ]
Badia, Lorenzo [1 ]
Verucchi, Gabriella [1 ]
Rossini, Giada [2 ]
Vocale, Caterina [2 ]
Gaibani, Paolo [2 ]
Viale, Pierluigi [1 ]
Attard, Luciano [1 ]
机构
[1] Alma Mater Studiorum Univ Bologna, S Orsola Malpighi Hosp, Unit Infect Dis, Dept Med & Surg Sci, Via G Massarenti 11, I-40138 Bologna, Italy
[2] Alma Mater Studiorum Univ Bologna, S Orsola Malpighi Hosp, Unit Microbiol, Dept Expt Diagnost & Specialty Med, Bologna, Italy
关键词
Coronavirus; HIV; Comorbidity; Pneumonia; Protease inhibitors;
D O I
10.1007/s15010-020-01492-7
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Background Since the end of February 2020, the Coronavirus Disease 2019 (COVID-19) outbreak rapidly spread throughout Italy and other European countries, but limited information has been available about its characteristics in HIV-infected patients. Methods We have described a case series of patients with HIV infection and COVID-19 diagnosed at the S.Orsola Hospital (Bologna, Italy) during March and April, 2020. Results We reported a case series of 26 HIV-infected patients with COVID-19. Nineteen subjects were men, the median age was 54 years, 73% of patients had one or more comorbidities. Only 5 patients with interstitial pneumonia were hospitalized, but there were no admissions to intensive care unit and no deaths. Conclusions In our experience, COVID-19 associated with HIV infection had a clinical presentation comparable to the general population and was frequently associated with chronic comorbidities.
引用
收藏
页码:333 / 337
页数:5
相关论文
共 19 条
[1]   COVID-19 in patients with HIV: clinical case series [J].
Blanco, Jose L. ;
Ambrosioni, Juan ;
Garcia, Felipe ;
Martinez, Esteban ;
Soriano, Alex ;
Mallolas, Josep ;
Miro, Jose M. .
LANCET HIV, 2020, 7 (05) :E314-E316
[2]  
Cao B, 2020, NEW ENGL J MED, V382, P1787, DOI [10.1056/NEJMoa2001282, 10.1056/NEJMc2008043]
[3]   Potential impact of COVID-19 in people living with HIV: experience from previous 21st century coronaviruses epidemics [J].
Dauby, Nicolas .
AIDS, 2020, 34 (08) :1255-1256
[4]   Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis [J].
Fu, Leiwen ;
Wang, Bingyi ;
Yuan, Tanwei ;
Chen, Xiaoting ;
Ao, Yunlong ;
Fitzpatrick, Thomas ;
Li, Peiyang ;
Zhou, Yiguo ;
Lin, Yi-fan ;
Duan, Qibin ;
Luo, Ganfeng ;
Fan, Song ;
Lu, Yong ;
Feng, Anping ;
Zhan, Yuewei ;
Liang, Bowen ;
Cai, Weiping ;
Zhang, Lin ;
Du, Xiangjun ;
Li, Linghua ;
Shu, Yuelong ;
Zou, Huachun .
JOURNAL OF INFECTION, 2020, 80 (06) :656-665
[5]   Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy Early Experience and Forecast During an Emergency Response [J].
Grasselli, Giacomo ;
Pesenti, Antonio ;
Cecconi, Maurizio .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (16) :1545-1546
[6]   COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients [J].
Haerter, Georg ;
Spinner, Christoph D. ;
Roider, Julia ;
Bickel, Markus ;
Krznaric, Ivanka ;
Grunwald, Stephan ;
Schabaz, Farhad ;
Gillor, Daniel ;
Postel, Nils ;
Mueller, Matthias C. ;
Mueller, Markus ;
Roemer, Katja ;
Schewe, Knud ;
Hoffmann, Christian .
INFECTION, 2020, 48 (05) :681-686
[7]   Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China [J].
Huang, Chaolin ;
Wang, Yeming ;
Li, Xingwang ;
Ren, Lili ;
Zhao, Jianping ;
Hu, Yi ;
Zhang, Li ;
Fan, Guohui ;
Xu, Jiuyang ;
Gu, Xiaoying ;
Cheng, Zhenshun ;
Yu, Ting ;
Xia, Jiaan ;
Wei, Yuan ;
Wu, Wenjuan ;
Xie, Xuelei ;
Yin, Wen ;
Li, Hui ;
Liu, Min ;
Xiao, Yan ;
Gao, Hong ;
Guo, Li ;
Xie, Jungang ;
Wang, Guangfa ;
Jiang, Rongmeng ;
Gao, Zhancheng ;
Jin, Qi ;
Wang, Jianwei ;
Cao, Bin .
LANCET, 2020, 395 (10223) :497-506
[8]   SARS-CoV-2 and HIV [J].
Joob, Beuy ;
Wiwanitkit, Viroj .
JOURNAL OF MEDICAL VIROLOGY, 2020, 92 (09) :1415-1415
[9]   Patients of COVID-19 may benefit from sustained Lopinavir-combined regimen and the increase of Eosinophil may predict the outcome of COVID-19 progression [J].
Liu, Fang ;
Xu, Aifang ;
Zhang, Yan ;
Xuan, Weiling ;
Yan, Tingbo ;
Pan, Kenv ;
Yu, Wenyan ;
Zhang, Jun .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2020, 95 :183-191
[10]   Could HIV infection alter the clinical course of SARS-CoV-2 infection? When less is better [J].
Mascolo, Silvia ;
Romanelli, Antonio ;
Carleo, Maria Aurora ;
Esposito, Vincenzo .
JOURNAL OF MEDICAL VIROLOGY, 2020, 92 (10) :1777-1778