Isolation and structural identification of a novel fructan from Radix Codonopsis

被引：11

作者：

Li, Jiankuan ^{[1
]}

Wang, Yan ^{[1
]}

Zhang, Xia ^{[1
]}

Cao, Lingya ^{[1
,2
]}

Ji, Jiaojiao ^{[1
]}

Zheng, Qinghong ^{[1
]}

Gao, Jianping ^{[1
]}

机构：

[1] Shanxi Med Univ, Sch Pharmaceut Sci, Taiyuan, Peoples R China

[2] Shanxi Med Univ, Sch Basic Med Sci, Taiyuan, Peoples R China

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 2020年 / 39卷 / 04期

基金：

国家重点研发计划;

关键词：

Codonopsis pilosula; fructan; inulin; polysaccharide; INULIN-TYPE FRUCTANS; LEVAN; POLYSACCHARIDES;

D O I：

10.1080/07328303.2020.1772278

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Fructans are generally divided into two different types:beta-D-fructofuranosyl-(2 -> 1)-linked inulin and beta-D-fructofuranosyl-(2 -> 6)-linked levan. Previously, Radix Codonopsis was found to be rich in inulin type of fructans with low molecular weight (<5000 Da). In this study, a novel macromolecular fructan with a molecular weight of 1.70 x 10(3)KD was isolated from Radix Codonopsis, and its homogeneity was shown to be a single peak by high performance gel permeation chromatography (HPGPC), and its structure was confirmed to contain a new type of linkage,alpha-D-fructofuranosyl-(2 -> 3)-beta-D-fructofuranosyl linkage, by 1D- and 2D-nuclear magnetic resonance (NMR).

引用

页码：163 / 174

页数：12