Using transcranial magnetic stimulation methods to probe connectivity between motor areas of the brain

被引：65
作者：
Rothwell, John C. [1 ]
机构：
[1] UCL Inst Neurol, London WC1N 3BG, England
来源：
HUMAN MOVEMENT SCIENCE | 2011年 / 30卷 / 05期
关键词：
Magnetic stimulation; Motor cortex; VENTRAL PREMOTOR CORTEX; CONCURRENT TMS-FMRI; DORSAL PREMOTOR; HUMANS; FACILITATION; PLASTICITY; OUTPUTS; MODULATION; MECHANISMS; SELECTION;
D O I：
10.1016/j.humov.2010.07.007
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Transcranial magnetic stimulation is increasingly used as a tool to explore cortical motor function in healthy subjects and in patients with neurological disease or injury. This review describes a "twin coil" TMS approach that allows investigation of time related changes in functional connectivity between primary motor cortex and other areas in preparation for a forthcoming movement. Investigations into premotor-motor interactions show that these are specific to the type of task that is performed as well as the muscles used to control the movement, allowing us to monitor information flow within motor networks with millisecond time resolution. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码：906 / 915
页数：10
相关论文
共 31 条
[1]   Inhibitory and facilitatory connectivity from ventral premotor to primary motor cortex in healthy humans at rest - A bifocal TMS study [J].
Baeumer, T. ;
Schippling, S. ;
Kroeger, J. ;
Zittel, S. ;
Koch, G. ;
Thomalla, G. ;
Rothwell, J. C. ;
Siebner, H. R. ;
Orth, M. ;
Muenchau, A. .
CLINICAL NEUROPHYSIOLOGY, 2009, 120 (09) :1724-1731
[2]   Magnetic stimulation of human premotor or motor cortex produces interhemispheric facilitation through distinct pathways [J].
Baeumer, Tobias ;
Bock, Franka ;
Koch, Giacomo ;
Lange, Ruediger ;
Rothwell, John C. ;
Siebner, Hartwig R. ;
Muenchau, Alexander .
JOURNAL OF PHYSIOLOGY-LONDON, 2006, 572 (03) :857-868
[3]  
BARKER AT, 1991, ELECTROEN CLIN NEURO, P227
[4]  
BARKER AT, 1985, LANCET, V1, P1106
[5]   Mapping causal interregional influences with concurrent TMS-fMRI [J].
Bestmann, Sven ;
Ruff, Christian C. ;
Blankenburg, Felix ;
Weiskopf, Nikolaus ;
Driver, Jon ;
Rothwell, John C. .
EXPERIMENTAL BRAIN RESEARCH, 2008, 191 (04) :383-402
[6]   Facilitation from ventral premotor cortex of primary motor cortex outputs to macaque hand muscles [J].
Cerri, G ;
Shimazu, H ;
Maier, MA ;
Lemon, RN .
JOURNAL OF NEUROPHYSIOLOGY, 2003, 90 (02) :832-842
[7]   Neural correlates of mental rehearsal in dorsal premotor cortex [J].
Cisek, P ;
Kalaska, JF .
NATURE, 2004, 431 (7011) :993-996
[8]   Cortical mechanisms of action selection: the affordance competition hypothesis [J].
Cisek, Paul .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2007, 362 (1485) :1585-1599
[9]   Transcranial magnetic stimulation can be used to test connections to primary motor areas from frontal and medial cortex in humans [J].
Civardi, C ;
Cantello, R ;
Asselman, P ;
Rothwell, JC .
NEUROIMAGE, 2001, 14 (06) :1444-1453
[10]   Functional relevance of cross-modal plasticity in blind humans [J].
Cohen, LG ;
Celnik, P ;
PascualLeone, A ;
Corwell, B ;
Faiz, L ;
Dambrosia, J ;
Honda, M ;
Sadato, N ;
Gerloff, C ;
Catala, MD ;
Hallett, M .
NATURE, 1997, 389 (6647) :180-183
1234