A Blueprint for Advancing Genetics-Based Cancer Therapy

被引：53

作者：

Sellers, William R. ^{[1
]}

机构：

[1] Novartis Inst Biomed Res, Cambridge, MA 02139 USA

来源：

CELL | 2011年 / 147卷 / 01期

关键词：

RESISTANT PROSTATE-CANCER; FACTOR-H POLYMORPHISM; CHRONIC-PHASE; INHIBITOR; IMATINIB; MUTATION; PATHWAY;

D O I：

10.1016/j.cell.2011.09.016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In the era of next-generation sequencing, there are significant challenges to harnessing cancer genome information to develop novel therapies. Key research thrusts in both academia and industry will speed this transition, and lessons learned for cancer will more broadly shape the process for genetic contributions to the therapy of disease more broadly.

引用

页码：26 / 31

页数：6

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