Changing epidemiology of systemic fungal infections

被引:343
作者
Richardson, M. [1 ,2 ]
Lass-Floerl, C. [3 ]
机构
[1] Univ Helsinki, Haartman Inst, Dept Bacteriol & Immunol, FI-00014 Helsinki, Finland
[2] Univ Helsinki, Cent Hosp, Diagnost Lab, FI-00014 Helsinki, Finland
[3] Innsbruck Med Univ, Dept Hyg Social Med & Microbiol, Innsbruck, Austria
关键词
epidemiology; fungal infections; review; risk-factors;
D O I
10.1111/j.1469-0691.2008.01978.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Species of Candida and Aspergillus remain the most common causes of invasive fungal infections, but other yeasts and filamentous fungi are emerging as significant pathogens. Opportunistic yeast-like fungi and moulds such as Zygomycetes, Fusarium spp. and Scedosporium spp. are increasingly being recognised in patient groups such as those with leukaemia and in bone marrow transplant recipients. Recognition of these epidemiological changes is critical to patient care. The key elements in selecting an appropriate antifungal agent are the type of patient (solid-organ or stem-cell transplant), severity of immunosuppression, history of prolonged exposure to antifungal drugs, and knowledge of the genera and species of the infecting pathogen and its typical susceptibility pattern.
引用
收藏
页码:5 / 24
页数:20
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