A new Diels-Alder type adduct and two new flavones from the stem bark of Morus yunanensis Koidz

被引：23

作者：

Cui, Xi-Qiang

Wang, Lei

Yan, Ren-Yi

Tan, Yong-Xia

Chen, Ruo-Yun ^{[1
]}

Yu, De-Quan

机构：

[1] Chinese Acad Med Sci, Minist Educ, Key Lab Bioact Subst & Resources Utilizat Chinese, Beijing 100050, Peoples R China

[2] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

[3] Peking Union Med Coll, Beijing 100050, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2008年 / 10卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Morus yunanensis Koidz; Diels-Alder type adduct; flavone; cytotoxic;

D O I：

10.1080/10286020701833537

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Fractionation of the ethanolic extract of the stem bark of Morus yunanensis resulted in the isolation of a new Diels - Alder type adduct and two new flavones, named yunanensin A (1), yunanensol A (2) and yunanensol B (3), respectively, together with a known flavone (4). Their structures were determined on the basis of spectroscopic analysis and chemical methods. Among them, compound 1 showed moderate antioxidant and significant cytotoxic activities, and compound 2 showed potent anti-inflammatory activity.

引用

页码：315 / 318

页数：4

共 6 条

[1] Guangsangons F-J, anti-oxidant and anti-inflammatory Diels-Alder type adducts, from Morus macroura Miq. [J].

Dai, SJ ;

Ma, ZB ;

Wu, Y ;

Chen, RY ;

Yu, DQ .

PHYTOCHEMISTRY, 2004, 65 (23) :3135-3141

[2]

FUKAI T, 1985, CHEM PHARM BULL, V33, P3195

[3]

HANO Y, 1985, CHEM PHARM BULL, V33, P5294

[4] Five new Diels-Alder type adducts from the stem and root bark of Morus mongolica [J].

Kang, J ;

Chen, RY ;

Yu, DQ .

PLANTA MEDICA, 2006, 72 (01) :52-59

[5] Aromatase inhibitors from Broussonetia papyrifera [J].

Lee, D ;

Bhat, KPL ;

Fong, HHS ;

Farnsworth, NR ;

Pezzuto, JM ;

Kinghorn, AD .

JOURNAL OF NATURAL PRODUCTS, 2001, 64 (10) :1286-1293

[6] CONSTITUENTS OF THE CULTIVATED MULBERRY TREE .7. ISOLATION OF 3 NEW ISOPRENOID-FLAVANONES, KUWANON D, E, AND F FROM ROOT BARK OF MORUS-ALBA L [J].

NOMURA, T ;

FUKAI, T .

PLANTA MEDICA, 1981, 42 (01) :79-88

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