H2SO4-Promoted Synthesis of (E)-Stilbenes from Substituted Phenylacetones and Substituted Benzaldehydes Through Tandem Aldol-Grob Reaction

被引：2

作者：

Narender, T. ^{[1
]}

Reddy, K. Papi ^{[1
]}

Tiwari, Sriniwas ^{[1
]}

机构：

[1] Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226001, Uttar Pradesh, India

来源：

SYNTHETIC COMMUNICATIONS | 2011年 / 41卷 / 11期

关键词：

(E)-Stilbenes; H2SO4; phenylacetones; 1-phenylpropan-2-one; REACTION SEQUENCE; HECK REACTION; ALDEHYDE TOSYLHYDRAZONES; ORGANOZINC REAGENTS; CARBONYL-COMPOUNDS; ANTIMITOTIC AGENT; ANIL SYNTHESIS; DERIVATIVES; STILBENES; CATALYST;

D O I：

10.1080/00397911.2010.488309

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[image omitted] Stilbene derivates (stilbenoids) are present in plants and show a wide range of biological activities and potential therapeutic value. In continuation of our natural product synthesis program, an efficient, simple, and practical method has been developed to regioselectively synthesize (E)-stilbenes using H2SO4 as a catalyst in a short time (30-60s) at room temperature in good to excellent yields.

引用

页码：1572 / 1583

页数：12

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