We consider the existence of several different kinds of factors in 4-connected claw-free graphs. This is motivated by the following two conjectures which are in fact equivalent by a recent result of the third author. Conjecture 1 (Thomassen): Every 4-connected line graph is hamiltonian, i.e., has a connected 2-factor. Conjecture 2 (Matthews and Sumner): Every 4-connected claw-free graph is hamiltonian. We first show that Conjecture 2 is true within the class of hourglass-free graphs, i.e., graphs that do not contain an induced subgraph isomorphic to two triangles meeting in exactly one vertex. Next we show that a weaker form of Conjecture 2 is true, in which the conclusion is replaced by the conclusion that there exists a connected spanning subgraph in which each vertex has degree two or four. Finally we show that Conjectures 1 and 2 are equivalent to seemingly weaker conjectures in which the conclusion is replaced by the conclusion that there exists a spanning subgraph consisting of a bounded number of paths. (C) 2001 John Wiley & Sons, Inc. J Graph Theory 37: 125-136, 2001.