Chaotically Accelerated Polymerase Chain Reaction by Microscale Rayleigh-Benard Convection

被引：21

作者：

Muddu, Radha ^{[2
]}

Hassan, Yassin A. ^{[2
,3
]}

Ugaz, Victor M. ^{[1
]}

机构：

[1] Texas A&M Univ, Artie McFerrin Dept Chem Engn, College Stn, TX 77843 USA

[2] Texas A&M Univ, Dept Mech Engn, College Stn, TX 77843 USA

[3] Texas A&M Univ, Dept Nucl Engn, College Stn, TX 77843 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 13期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

analytical methods; biochemistry; chaos; DNA replication; microreactors; NATURAL-CONVECTION;

D O I：

10.1002/anie.201004217

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Going with the flow: DNA replication by the polymerase chain reaction (PCR) can proceed at a greatly accelerated rate when performed in the presence of a chaotic flow induced by microscale thermal convection (see picture). The consequences of these effects sharply contradict established design rules for chemistry involving coupled flow and reaction. © 2011 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3048 / 3052

页数：5

共 50 条

[31] Numerical investigation of Rayleigh-Benard convection in a cylinder of unit aspect ratio
Wang, Bo-Fu
Zhou, Lin
Jiang, Jin
Sun, De-Jun
FLUID DYNAMICS RESEARCH, 2016, 48 (01)
[32] Numerical simulation of the Rayleigh-Benard convection under the influence of magnetic fields
Yu, Xing-Xing
Zhang, Jie
Ni, Ming-Jiu
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 2018, 120 : 1118 - 1131
[33] Measuring the departures from the Boussinesq approximation in Rayleigh-Benard convection experiments
Kurtuldu, H.
Mischaikow, K.
Schatz, M. F.
JOURNAL OF FLUID MECHANICS, 2011, 682 : 543 - 557
[34] Energy-conserving model of hexagonal pattern in Rayleigh-Benard convection
Mondal, Hiya
Das, Alaka
FLUID DYNAMICS RESEARCH, 2022, 54 (01)
[35] Laminar Rayleigh-Benard convection of yield stress fluids in a square enclosure
Turan, Osman
Chakraborty, Nilanjan
Poole, Robert J.
JOURNAL OF NON-NEWTONIAN FLUID MECHANICS, 2012, 171 : 83 - 96
[36] Stability analysis of Rayleigh-Benard convection in a cylinder with internal heat generation
Wang, Bo-Fu
Zhou, Lin
Wan, Zhen-Hua
Ma, Dong-Jun
Sun, De-Jun
PHYSICAL REVIEW E, 2016, 94 (01)
[37] Three-dimensional simulation of Rayleigh-Benard convection in a rectangular cavity
Zhan, N. Y.
Yang, M.
Wang, Z. Y.
Li, L.
Zheng, Z. Z.
PROGRESS IN COMPUTATIONAL FLUID DYNAMICS, 2008, 8 (7-8): : 526 - 535
[38] A study of Rayleigh-Benard convection in hybrid nanoliquids with physically realistic boundaries
Kanchana, C.
Siddheshwar, P. G.
Zhao, Yi
EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS, 2019, 228 (12) : 2511 - 2530
[39] Rayleigh-Benard Convection in a Nanofluid Layer Using a Thermal Nonequilibrium Model
Agarwal, Shilpi
Rana, Puneet
Bhadauria, B. S.
JOURNAL OF HEAT TRANSFER-TRANSACTIONS OF THE ASME, 2014, 136 (12):
[40] Critical condition for Rayleigh-Benard convection of Bingham fluids in rectangular enclosures
Turan, O.
Yigit, S.
Chakraborty, N.
INTERNATIONAL COMMUNICATIONS IN HEAT AND MASS TRANSFER, 2017, 86 : 117 - 125

← 1 2 3 4 5 →