Fulminant subacute sclerosing panencephalitis (SSPE) presented with acute hemiparesis in a 13-year-old girl with perinatally acquired HIV infection

被引:2
作者
Vidhale, Tushar Ashok [1 ]
Gupta, Hemant R. [1 ]
Jaya, Rohan Prafulla [2 ]
Pustake, Manas [1 ]
机构
[1] Grant Med Coll & Sir JJ Grp Hosp, Gen Med, Mumbai, Maharashtra, India
[2] BGS Global Inst Med Sci, Dept Radiol, Bangalore, Karnataka, India
关键词
infection (neurology); HIV; AIDS; HUMAN-IMMUNODEFICIENCY-VIRUS; CHILD; MEASLES;
D O I
10.1136/bcr-2020-241205
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 13-year-old girl with perinatally acquired HIV infection was admitted to us with acute onset, right-sided hemiparesis of 30 days duration and right-sided myoclonic jerks of 2 days duration affecting the face, upper and lower limbs. On examination, she exhibited increased tone and a pyramidal pattern of weakness in her right upper and lower limbs, along with spontaneous multifocal myoclonic jerks in the affected area. IgG levels in the serum and cerebrospinal fluid for measles were significantly elevated. Brain MRI depicted T2-weighted-hyperintensities in the subcortical white matter. The electroencephalogram demonstrated evidence of lateralised long interval periodic discharges. This patient had no past behavioural problems or poor academic performance. This case underlines the fact that, though subacute sclerosing panencephalitis (SSPE) is a chronic disease, a rare fulminant form of SSPE might develop acutely and atypically, with an increased proclivity for HIV-infected patients.
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页数:10
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