Advances in mast cell biology

被引：10
|
作者：
Boyce, Joshua A. [1 ]
机构：
[1] Brigham & Womens Hosp, Dept Med, Div Allergy & Clin Immunol, Hale Bldg Transformat Med,Rm 5002V,60 Fenwood Rd, Boston, MA 02115 USA
来源：
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2022年 / 149卷 / 06期
关键词：
Mast cells; systemic mastocytosis; AERD; CRSwNP; Staphyloccocus; single cell genomics; Mas-related G-protein-coupled receptor 2; CHRONIC RHINOSINUSITIS; NASAL POLYPS; INFLAMMATION; MIDOSTAURIN; ACTIVATION; INHIBITORS; RESPONSES; BACTERIAL;
D O I：
10.1016/j.jaci.2022.03.029
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Mast cells (MCs) contribute prominently to all allergic diseases, yet are still poorly understood owing to their exclusive residence in tissues. Recently, the use of RNA-sequencing, proteomics, and other technological advances have accelerated the acquisition of new knowledge. This includes an expanded definition of MC heterogeneity and developmental origins, previously unrecognized functions for MCs, discoveries of genetic causes of MC-related disorders, the introduction of new therapies for clonal MC disease, and the identification of new potential target for treatments. This issue of Advances addresses key studies from 2020 to 2021.
引用
收藏
页码：1919 / 1925
页数：7
相关论文
共 50 条
  • [31] The ingenious mast cell: Contemporary insights into mast cell behavior and function
    Dahlin, Joakim S.
    Maurer, Marcus
    Metcalfe, Dean D.
    Pejler, Gunnar
    Sagi-Eisenberg, Ronit
    Nilsson, Gunnar
    ALLERGY, 2022, 77 (01) : 83 - 99
  • [32] TNF-α Regulates Mast Cell Functions by Inhibiting Cell Degranulation
    Gao, Yuwei
    Xu, Baixue
    Zhang, Peng
    He, Yanlong
    Liang, Xin
    Liu, Jianwen
    Li, Jiyu
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2017, 44 (02) : 751 - 762
  • [33] Neuroimmune Biology of Mast Cells
    Salinas, Eva
    ADVANCES IN NEUROIMMUNE BIOLOGY, 2012, 3 (01) : 57 - 72
  • [34] Mast cell mediators
    Blank, U.
    Vitte, J.
    REVUE FRANCAISE D ALLERGOLOGIE, 2015, 55 (01): : 31 - 38
  • [35] Mast cell infiltrates in vulvodynia represent secondary and idiopathic mast cell hyperplasias
    Regauer, Sigrid
    Eberz, Barbara
    Beham-Schmid, Christine
    APMIS, 2015, 123 (05) : 452 - 456
  • [36] Mast cells, basophils and B cell connection network
    Merluzzi, Sonia
    Betto, Elena
    Ceccaroni, Alice Amaranta
    Magris, Raffaella
    Giunta, Marina
    Mion, Francesca
    MOLECULAR IMMUNOLOGY, 2015, 63 (01) : 94 - 103
  • [37] Mast Cell-Biomaterial Interactions and Tissue Repair
    Ozpinar, Emily W.
    Frey, Ariana L.
    Cruse, Glenn
    Freytes, Donald O.
    TISSUE ENGINEERING PART B-REVIEWS, 2021, 27 (06) : 590 - 603
  • [38] Current Advances in Follicular Regulatory T-Cell Biology
    Ghosh, Sadashib
    Leavenworth, Jianmei W.
    CRITICAL REVIEWS IN IMMUNOLOGY, 2022, 42 (02) : 35 - 47
  • [39] Nitric oxide: a regulator of mast cell activation and mast cell-mediated inflammation
    Coleman, JW
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2002, 129 (01) : 4 - 10
  • [40] Toll-like receptors 3 ligation directly and indirectly affects mast cell cysteinyl leukotriene generation
    Witczak, Piotr
    Pietrzak, Anna
    Slodka, Aleksandra
    Brzezinska-Blaszczyk, Ewa
    CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY, 2013, 38 (03) : 343 - 348
12345