Is Maintenance of Sinus Rhythm of Value in Patients with Atrial Fibrillation and Heart Failure?

被引：2

作者：

Sadek, Mouhannad M. ^{[1
]}

Skanes, Allan ^{[2
]}

Tang, Anthony S. L. ^{[2
]}

机构：

[1] Univ Ottawa, Arrhythmia Serv, Div Cardiol, Heart Inst, Ottawa, ON, Canada

[2] Western Univ, Univ Hosp, Schulich Sch Med & Dent, 339 Windermere Rd,C6-116, London, ON, Canada

来源：

CURRENT CARDIOLOGY REPORTS | 2022年 / 24卷 / 10期

基金：

加拿大健康研究院;

关键词：

Atrial fibrillation; Heart failure; Catheter ablation; Rate control; Rhythm control; CATHETER ABLATION; RANDOMIZED-TRIAL; MORTALITY; STRATEGIES; DOFETILIDE; MANAGEMENT; DISEASE;

D O I：

10.1007/s11886-022-01743-z

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose of Review Heart failure (HF) and atrial fibrillation (AF) frequently co-exist, with the prevalence of AF increasing in patients with more advanced HF symptoms. When present, AF increases morbidity and mortality in patients with HF. The purpose of this review is to examine emerging evidence addressing the value of restoration and maintenance of sinus rhythm in patients with HF. Recent Findings Earlier trials comparing a rhythm control strategy with antiarrhythmic drugs have failed to demonstrate benefit in patients with HF and reduced ejection fraction. More recent trials, including the recently published RAFT-AF, utilizing catheter ablation for rhythm control, have shown greater promise, possibly due to reduced medication-related side effects and higher efficacy in maintaining sinus rhythm. A strategy of sinus rhythm maintenance with catheter ablation appears to improve mortality, reduce HF events and improve quality of life in patients with AF and HF.

引用

页码：1227 / 1231

页数：5

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