Ion-mediated conformational switches

被引：88

作者：

Knipe, Peter C. ^{[1
]}

Thompson, Sam ^{[1
]}

Hamilton, Andrew D. ^{[1
]}

机构：

[1] Univ Oxford, Dept Chem, Chem Res Lab, Oxford OX1 3TA, England

来源：

CHEMICAL SCIENCE | 2015年 / 6卷 / 03期

关键词：

MECHANOSENSITIVE CHANNEL; MOLECULAR RECOGNITION; ANION RECOGNITION; HELICITY CONTROL; MOTION; SELECTIVITY; RECEPTORS; CAVITANDS; INVERSION; FOLDAMERS;

D O I：

10.1039/c4sc03525a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Molecular switches are ubiquitous in Nature and provide the basis of many forms of transport and signalling. Single synthetic molecules that change conformation, and thus function, reversibly in a stimulus-dependent manner are of great interest not only to chemists but society in general; myriad applications exist in storage, display, sensing and medicine. Here we describe recent developments in the area of ion-mediated switching.

引用

页码：1630 / 1639

页数：10

共 81 条

[1] A Molecular Leverage for Helicity Control and Helix Inversion [J].

Akine, Shigehisa ;

Hotate, Sayaka ;

Nabeshima, Tatsuya .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (35) :13868-13871

[2] Metal-switching and self-inclusion of functional cavitands [J].

Amrhein, P ;

Shivanyuk, A ;

Johnson, DW ;

Rebek, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (35) :10349-10358

[3] Resorcin[4]arene cavitand-based molecular switches [J].

Azov, VA ;

Beeby, A ;

Cacciarini, M ;

Cheetham, AG ;

Diederich, F ;

Frei, M ;

Gimzewski, JK ;

Gramlich, V ;

Hecht, B ;

Jaun, B ;

Latychevskaia, T ;

Lieb, A ;

Lill, Y ;

Marotti, F ;

Schlegel, A ;

Schlittler, RR ;

Skinner, PJ ;

Seiler, P ;

Yamakoshi, Y .

ADVANCED FUNCTIONAL MATERIALS, 2006, 16 (02) :147-156

[4] NMR investigations into the vase-kite conformational switching of resorcin[4]arene cavitands [J].

Azov, VA ;

Jaun, B ;

Diederich, F .

HELVETICA CHIMICA ACTA, 2004, 87 (02) :449-462

[5]

Balzani V, 2000, ANGEW CHEM INT EDIT, V39, P3348, DOI 10.1002/1521-3773(20001002)39:19<3348::AID-ANIE3348>3.0.CO

[6]

2-X

[7] Dynamic chemical devices: Modulation of contraction/extension molecular motion by coupled-ion binding/pH change-induced structural switching [J].

Barboiu, M ;

Lehn, JM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (08) :5201-5206

[8] The ON/OFF switching by metal ions of the "Sergeants and Soldiers" chiral amplification effect on helical poly(phenylacetylene)s [J].

Bergueiro, Julian ;

Freire, Felix ;

Wendler, Edison P. ;

Seco, Jose M. ;

Quinoa, Emilio ;

Riguera, Ricardo .

CHEMICAL SCIENCE, 2014, 5 (06) :2170-2176

[9] trans-2-aminocyclohexanol as a pH-sensitive conformational switch in lipid amphiphiles [J].

Brazdova, Barbora ;

Zhang, Ningrong ;

Samoshin, Vyacheslav V. ;

Guo, Xin .

CHEMICAL COMMUNICATIONS, 2008, (39) :4774-4776

[10] Making molecular machines work [J].

Browne, Wesley R. ;

Feringa, Ben L. .

NATURE NANOTECHNOLOGY, 2006, 1 (01) :25-35

← 1 2 3 4 5 6 7 8 9 →