Azasteroids as antifungals

被引：67
作者：
Burbiel, J [1 ]
Bracher, F [1 ]
机构：
[1] Univ Munich, Dept Pharm, Zentrum Pharmaforsch, D-81377 Munich, Germany
来源：
STEROIDS | 2003年 / 68卷 / 7-8期
关键词：
azasteroid; steroid; A25822B; ergosterol biosynthesis; antifungal;
D O I：
10.1016/S0039-128X(03)00080-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Azasteroids and derivatives thereof with antifungal potential are reviewed. Special emphasis is put on steroids with nitrogen as part of the steroidal framework, natural substances, and lines of development emerging from them. (C) 2003 Elsevier Inc. All rights reserved.
引用
收藏
页码：587 / 594
页数：8
相关论文
共 47 条
  • [1] ABOULENEIN HY, 1974, PHARM ACTA HELV, V49, P320
  • [2] AHMAD MS, 1974, INDIAN J CHEM, V12, P1323
  • [3] CHEMISTRY AND BIOLOGY OF NOVEL AMINE FUNGICIDES - ATTEMPTS TO IMPROVE THE ANTIFUNGAL ACTIVITY OF FENPROPIMORPH
    AKERS, A
    AMMERMANN, E
    BUSCHMANN, E
    GOTZ, N
    HIMMELE, W
    LORENZ, G
    POMMER, EH
    RENTZEA, C
    ROHL, F
    SIEGEL, H
    ZIPPERER, B
    SAUTER, H
    ZIPPLIES, M
    [J]. PESTICIDE SCIENCE, 1991, 31 (04): : 521 - 538
  • [4] BACK TG, 1995, SYNTHESIS-STUTTGART, P162
  • [5] BarrettBee K, 1995, ACTA BIOCHIM POL, V42, P465
  • [6] BARTH M, 1996, J MED CHEM, V38, P2302
  • [7] PARTIAL SYNTHESIS OF THE STEROIDIC CHROMOPHORE 14A-AZA-D-HOMO-8,14A-DIENE PRESENT IN THE ANTIBIOTIC A-25822-B
    BARTON, DHR
    LUSINCHI, X
    MENENDEZ, AM
    MILLIET, P
    [J]. TETRAHEDRON, 1983, 39 (13) : 2201 - 2205
  • [8] Synthesis of 6(α,β)-aminocholestanols as ergosterol biosynthesis inhibitors
    Beuchet, P
    El kihel, L
    Dherbomez, M
    Charles, G
    Letourneux, Y
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (24) : 3627 - 3630
  • [9] NEW AZASTEROIDAL ANTIFUNGAL ANTIBIOTICS FROM GEOTRICHUM-FLAVO-BRUNNEUM .1. DISCOVERY AND FERMENTATION STUDIES
    BOECK, LD
    HOEHN, MM
    WESTHEAD, JE
    WOLTER, RK
    THOMAS, DN
    [J]. JOURNAL OF ANTIBIOTICS, 1975, 28 (02) : 95 - 101
  • [10] ANTIBACTERIAL ACTIVITY OF 15-AZASTEROIDS ALONE AND IN COMBINATION WITH ANTIBIOTICS
    CHESNUT, RW
    DURHAM, NN
    BROWN, RA
    MAWDSLEY, EA
    BERLIN, KD
    [J]. STEROIDS, 1976, 27 (04) : 525 - 541
12345