Activity of the Janus kinase inhibitor ruxolitinib in chronic lymphocytic leukemia: results of a phase II trial

被引:27
作者
Spaner, David E. [1 ,2 ,3 ,4 ,5 ]
Wang, Guizhei [1 ]
McCaw, Lindsay [1 ]
Li, Yanmei [1 ]
Disperati, Patricia [6 ]
Cussen, Mary-Ann [3 ]
Shi, Yonghong [1 ]
机构
[1] Sunnybrook Res Inst, Biol Platform, Toronto, ON, Canada
[2] Univ Toronto, Dept Med Biophys, Toronto, ON M5S 1A1, Canada
[3] Sunnybrook Odette Canc Ctr, Toronto, ON, Canada
[4] Univ Toronto, Dept Med, Toronto, ON M5S 1A1, Canada
[5] Univ Toronto, Dept Immunol, Toronto, ON M5S 1A1, Canada
[6] Toronto East Gen Hosp, Toronto, ON, Canada
关键词
chronic lymphocytic leukemia; Janus Kinases; STAT3; Ruxolitinib; Ibrutinib; Kinase inhibitors; phosphoproteome; FOLLOW-UP; RESISTANCE; THERAPY; CELLS; CLL;
D O I
10.3324/haematol.2015.135418
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:4
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