Synthesis of (±)-15-deoxy-Δ12,14-prostaglandin J2 and Δ12-prostaglandin J2 15-acetate methyl esters

被引：3

作者：

Vostrikov, N. S. ^{[1
]}

Lobko, I. F. ^{[1
]}

Ishimova, D. U. ^{[2
]}

Miftakhov, M. S. ^{[1
]}

机构：

[1] Russian Acad Sci, Ufa Res Ctr, Inst Organ Chem, Ufa 450054, Bashkortostan, Russia

[2] Bashkir State Univ, Ufa 450074, Bashkortostan, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 51卷 / 01期

关键词：

CYCLOPENTENONE PROSTAGLANDINS; 15-DEOXY-DELTA(12,14)-PGJ(2); DELTA(12)-PGJ(2);

D O I：

10.1134/S1070428015010017

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthetic approach to 15-deoxy-Delta(12,14)-prostaglandin J(2) and related compounds starting from Corey (+/-)-lactone diol has been developed. The key stage of this approach includes synthesis of a prostaglandin derivative possessing leaving groups in positions 9, 13, and 15 and their subsequent elimination by the action of an organic base.

引用

页码：1 / 9

页数：9

共 15 条

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