Disturbed sleep in cluster headache is not the result of transient processes associated with the cluster period

被引:20
作者
Lund, N. L. T. [1 ]
Snoer, A. H. [1 ]
Petersen, A. S. [1 ]
Beske, R. P. [1 ]
Jennum, P. J. [2 ]
Jensen, R. H. [1 ]
Barloese, M. C. J. [1 ,3 ]
机构
[1] Rigshosp Glostrup, Dept Neurol, Danish Headache Ctr, Glostrup, Denmark
[2] Rigshosp Glostrup, Danish Ctr Sleep Med, Glostrup, Denmark
[3] Hvidovre Univ Hosp, Dept Clin Physiol & Nucl Med, Ctr Funct & Diagnost Imaging, Copenhagen, Denmark
关键词
case control; cluster headache; insomnia; polysomnography; rapid eye movement sleep; sleep; sleep apnea; APNEA; INSOMNIA;
D O I
10.1111/ene.13820
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background and purpose Cluster headache (CH) is characterized by severe, unilateral attacks of pain and a high nocturnal attack burden. It remains unknown whether perturbations of sleep are solely present during the CH bout. Therefore, we aimed to investigate differences in sleep between the bout and remission period in patients with episodic CH and, secondly, to compare patients in the two phases with controls. Methods Patients with episodic CH (aged 18-65 years), diagnosed according to the International Classification of Headache Disorders 2nd edition, were admitted for polysomnography at the Danish Center for Sleep Medicine in bout and in remission. The macrostructure of sleep, including arousals, breathing parameters, limb movements and periodic limb movements, was compared with 25 age-, sex- and body mass index-matched healthy controls. Results There were no differences in any of the sleep parameters for patients in bout (n = 32) compared with patients in remission (n = 23). Attacks were unrelated to sleep stages, presence of apnea episodes, periodic limb movements, limb movements and arousals. In bout, patients had longer sleep latency (18.8 vs. 11.7 min, P < 0.05) and rapid eye movement sleep latency (1.7 vs. 1.2 h, P < 0.05) than controls and sleep efficiency was lower (82.5% vs. 86.5%, P < 0.05). Patients in remission only had a longer sleep latency compared with controls (17.5 vs. 11.7 min, P < 0.01). Conclusions The results support the presence of a continuing or slowly recovering disturbance of sleep outside the bout rather than a disturbance occurring secondary to attacks. Further, we confirm that there is no relation between CH attacks and specific sleep stages or between CH and breathing parameters.
引用
收藏
页码:290 / 298
页数:9
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[41]   Cluster headache associated with parainfluenza virus, preceded and succeeded by migraine [J].
Blanchard, BM .
HEADACHE, 1998, 38 (02) :132-134
[42]   cluster headache attacks in a woman previously struck by lightning -: Pathophysiology of the latent period [J].
Moraes Valenca, Marcelo ;
da Silva, Wilson Farias ;
Andrade-Valenca, Luciana Patrizia A. ;
Bordini, Carlos A. ;
Speciali, Jos Geraldo .
ARQUIVOS DE NEURO-PSIQUIATRIA, 2007, 65 (2A) :352-354
[43]   White blood cell SPECT during active period of cluster headache and in remission [J].
Steinberg, A. ;
Axelsson, R. ;
Idestrom, L. ;
Muller, S. ;
Remahl, A. I. M. Nilsson .
EUROPEAN JOURNAL OF NEUROLOGY, 2012, 19 (02) :220-225
[44]   Low CSF hypocretin-1 levels are associated with cluster headache [J].
Barloese, M. ;
Jennum, P. ;
Lund, N. ;
Knudsen, S. ;
Gammeltoft, S. ;
Jensen, R. .
JOURNAL OF HEADACHE AND PAIN, 2014, 15
[45]   Reduced CSF hypocretin-1 levels are associated with cluster headache [J].
Barloese, Mads ;
Jennum, Poul ;
Lund, Nunu ;
Knudsen, Stine ;
Gammeltoft, Steen ;
Jensen, Rigmor .
CEPHALALGIA, 2015, 35 (10) :869-876
[46]   Cerebrospinal fluid hypocretin-1 levels during the active period of cluster headache [J].
Cevoli, Sabina ;
Pizza, Fabio ;
Grimaldi, Daniela ;
Nicodemo, Marianna ;
Favoni, Valentina ;
Pierangeli, Giulia ;
Valko, Philipp O. ;
Baumann, Christian R. ;
Montagna, Pasquale ;
Bassetti, Claudio L. ;
Cortelli, Pietro .
CEPHALALGIA, 2011, 31 (08) :973-976
[47]   Cluster Headache is Associated With the Alcohol Dehydrogenase 4 (ADH4) Gene [J].
Rainero, Innocenzo ;
Rubino, Elisa ;
Gallone, Salvatore ;
Fenoglio, Pierpaola ;
Negro, Elisa ;
De Martino, Paola ;
Savi, Lidia ;
Pinessi, Lorenzo .
HEADACHE, 2010, 50 (01) :92-98
[48]   A genetic CLOCK variant associated with cluster headache causing increased mRNA levels [J].
Fourier, Carmen ;
Ran, Caroline ;
Zinnegger, Margret ;
Johansson, Anne-Sofie ;
Sjostrand, Christina ;
Waldenlind, Elisabet ;
Steinberg, Anna ;
Belin, Andrea Carmine .
CEPHALALGIA, 2018, 38 (03) :496-502
[49]   Cluster Headache and Associated Risk Factors: A Systemic Review and Meta-Analysis [J].
Elbadawi, Abdulateef Sayed A. ;
Albalawi, Abdulmajeed Faisal A. ;
Alghannami, Ali K. ;
Alsuhaymi, Fahad S. ;
Alruwaili, Atheer M. ;
Almaleki, Faisal A. ;
Almutairi, Maram F. ;
Almubaddil, Khuloud H. ;
Qashqari, Maryam, I .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (11)
[50]   Beta-oscillations in the posterior hypothalamus are associated with spontaneous cluster headache attack [J].
Wido Nager ;
Thomas F. Münte ;
Josep Marco-Pallares ;
Marcus Heldmann ;
Reinhard Dengler ;
Hans Holger Capelle ;
Götz Lütjens ;
Joachim K. Krauss .
Journal of Neurology, 2010, 257 :1743-1744