Osteoinduction by calcium phosphate biomaterials

被引：303

作者：

Yuan, HP

Yang, ZJ

Li, YB

Zhang, XD

De Bruijn, JD

De Groot, K

机构：

[1] IsoTis BV, NL-3723 MB Bilthoven, Netherlands

[2] Sichuan Univ, Inst Mat Sci & Technol, Chengdu 610064, Peoples R China

[3] Leiden Univ, Biomat Res Grp, NL-2300 RA Leiden, Netherlands

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 1998年 / 9卷 / 12期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1023/A:1008950902047

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Different materials were implanted in muscles of dogs to study the osteoinduction of calcium phosphate biomaterials. Bone formation was only seen in calcium phosphate biomaterials with micropores, and could be found in hydroxyapatite (HA) ceramic, tricalcium phosphate/hydroxyapatite ceramic (BCP), beta-TCP ceramic and calcium phosphate cement. The osteoinductive potential was different in different materials. The results indicate that osteoinduction can be a property of calcium phosphate biomaterials when they exhibit specific chemical and structural characteristics. (C) 1998 Kluwer Academic Publishers.

引用

页码：723 / 726

页数：4

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