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X-ray powder diffraction analysis of abacavir hemisulfate
被引:2
|作者:
Monger, G
Varlashkin, P
机构:
[1] GlaxoSmithKline Inc, Res Triangle Pk, NC 27707 USA
[2] Metr Inc, Greenville, NC 27834 USA
关键词:
abacavir hemisulfate;
powder X-ray diffraction;
powder X-ray pattern;
HIV;
D O I:
10.1154/1.1948390
中图分类号:
TB3 [工程材料学];
学科分类号:
0805 ;
080502 ;
摘要:
The room temperature powder pattern of abacavir hemisulfate (anti-HIV reverse transcriptase compound) was indexed using 2 theta values obtained from a powder pattern spiked with an internal standard. The resulting unit cell values for the monoclinic I2 cell [nonstandard setting of C2 (No. 5)] are a = 13.278(1) angstrom, b = 8.437(1) angstrom, c = 14.259(2) angstrom, beta = 93.87(1)degrees. There are two formula units [(C14H16N6O)(2).H2SO4] per unit cell and D-x = 1.390 g/cm(3). (c) 2005 International Centre for Diffraction Data.
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页码:241 / 245
页数:5
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