miRNAs and lncRNAs: Potential Non-Invasive Biomarkers for Endometriosis

被引:18
|
作者
Maier, Ioana Maria [1 ]
Maier, Adrian Cornel [1 ,2 ]
机构
[1] Emergency Mil Hosp, Galati 800150, Romania
[2] Univ Galatzi, Fac Med & Pharm, Galati 800008, Romania
关键词
miRNAs; lncRNAs; endometriosis; EUTOPIC SECRETORY ENDOMETRIUM; CIRCULATING MICRORNAS; NONCODING RNAS; PLASMA; WOMEN; SERUM; BIOGENESIS; PATHWAYS;
D O I
10.3390/biomedicines9111662
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Many studies have tried to understand the mechanism of endometriosis and its manner of manifestation. However, the only method of diagnosis considered as the gold standard in endometriosis is an invasive method called exploratory laparoscopy. Hence, there is a need to identify non-invasive or minimally invasive methods to minimize patients' suffering, thus increasing their addressability at the earliest possible staging of the disease, and to diagnose this condition as soon as possible. miRNAs (microRNAs) and lncRNAs (long-noncoding RNAs) are potential non-invasive diagnostic methods for endometriosis. Multiple clinical trials indicate that miRNA can be used as a non-invasive method in the diagnosis and differentiation of endometriosis stages.
引用
收藏
页数:11
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