Palladium-catalyzed stereoselective synthesis of 3-(aminomethylene)-oxindoles

被引：21

作者：

Bararjanian, Morteza ^{[1
]}

Hosseinzadeh, Saeedeh ^{[1
]}

Balalaie, Saeed ^{[1
]}

Bijanzadeh, Hamid Reza ^{[2
]}

Wolf, Eckardt ^{[3
]}

机构：

[1] KN Toosi Univ Technol, Peptide Chem Res Ctr, Tehran, Iran

[2] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

[3] Tofigh Daru Res & Eng Co, Tehran 37515375, Iran

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 26期

关键词：

Carbopalladative cyclization; Buchwald reaction; 3-(Aminoarylmethylene)-oxindoles; Active acetylenic compounds; Stereoselective synthesis; ONE-POT SYNTHESIS; MULTICOMPONENT REACTIONS; HETEROCYCLIC SCAFFOLDS; BIARYL ETHER; RAPID ACCESS; UGI-ADDUCTS; CYCLIZATIONS; MACROCYCLES; INHIBITOR; INDOLONES;

D O I：

10.1016/j.tetlet.2011.04.071

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient palladium-catalyzed protocol for the stereoselective synthesis of 3-(aminoarylmethylene)-oxindoles has been developed. In this approach, Ugi-4-component reaction adducts were used as starting materials for carbopalladative cyclization-Buchwald reaction sequences. (C) 2011 Published by Elsevier Ltd.

引用

页码：3329 / 3332

页数：4

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