ERS statement on standardisation of cardiopulmonary exercise testing in chronic lung diseases

被引：201

作者：

Radtke, Thomas ^{[1
,2
,3
]}

Crook, Sarah ^{[1
]}

Kaltsakas, Georgios ^{[4
,5
]}

Louvaris, Zafeiris ^{[6
]}

Berton, Danilo ^{[7
]}

Urquhart, Don S. ^{[8
]}

Kampouras, Asterios ^{[9
]}

Rabinovich, Roberto A. ^{[10
,11
]}

Verges, Samuel ^{[12
]}

Kontopidis, Dimitris ^{[13
]}

Boyd, Jeanette ^{[14
]}

Tonia, Thomy ^{[15
]}

Langer, Daniel ^{[6
,16
]}

De Brandt, Jana ^{[17
]}

Goertz, Yvonne M. J. ^{[18
]}

Burtin, Chris ^{[17
]}

Spruit, Martijn A. ^{[17
,18
,19
]}

Braeken, Dionne C. W. ^{[18
]}

Dacha, Sauwaluk ^{[6
,16
,20
]}

Franssen, Frits M. E. ^{[18
,19
]}

Laveneziana, Pierantonio ^{[21
,22
]}

Eber, Ernst ^{[23
]}

Troosters, Thierry ^{[24
,25
]}

Neder, J. Alberto ^{[26
,27
]}

Puhan, Milo A. ^{[1
]}

Casaburi, Richard ^{[28
]}

Vogiatzis, Ioannis ^{[5
,29
]}

Hebestreit, Helge ^{[30
]}

机构：

[1] Univ Zurich, Biostat & Prevent Inst, Dept Epidemiol, Zurich, Switzerland

[2] Univ Zurich, Div Occupat & Environm Med, Epidemiol Biostat & Prevent Inst, Zurich, Switzerland

[3] Univ Hosp Zurich, Zurich, Switzerland

[4] Guys & St Thomas NHS Fdn Trust, St Thomas Hosp, Lane Fox Resp Serv, London, England

[5] Natl & Kapodistrian Univ Athens, Dept Resp Med 1, Athens, Greece

[6] Univ Hosp Leuven, Fac Kinesiol & Rehabil Sci, Dept Rehabil Sci KU Leuven, Div Resp Rehabil, Leuven, Belgium

[7] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Unidade Fisiol Pulm, Porto Alegre, RS, Brazil

[8] Royal Hosp Sick Children, Dept Paediat Resp & Sleep Med, Edinburgh, Midlothian, Scotland

[9] 424 Gen Mil Hosp, Paediat Dept, Thessaloniki, Greece

[10] Univ Edinburgh, MRC Ctr Inflammat Res, Queens Med Res Inst, ELEGI Colt Lab, Edinburgh, Midlothian, Scotland

[11] Royal Infirm Edinburgh NHS Trust, Resp Med Dept, Edinburgh, Midlothian, Scotland

[12] Grenoble Alpes Univ, HP2 Lab, INSERM, Grenoble, France

[13] Hellen Cyst Fibrosis Assoc, Athens, Greece

[14] European Lung Fdn, Sheffield, S Yorkshire, England

[15] Univ Bern, Inst Social & Prevent Med, Bern, Switzerland

[16] Univ Hosp Leuven, Resp Rehabil & Resp Div, Leuven, Belgium

[17] Hasselt Univ, Fac Rehabil Sci, REVAL Rehabil Res Ctr, BIOMED Biomed Res Inst, Diepenbeek, Belgium

[18] Ctr Expertise Chron Organ Failure, Dept Res & Educ, CIRO, Horn, Netherlands

[19] Maastricht Univ, NUTRIM Sch Nutr & Translat Res Metab, Dept Resp Med, Med Ctr, Maastricht, Netherlands

[20] Chiang Mai Univ, Fac Associated Med Sci, Dept Phys Therapy, Chiang Mai, Thailand

[21] Sorbonne Univ, UMRS1158, INSERM, Neurophysiol Resp Expt & Clin, Paris, France

[22] Grp Hosp Pitie Salpetriere Charles Foix, AP HP, Serv Explorat Fonct Respirat Exercice & Dyspnee D, Paris, France

[23] Med Univ Graz, Dept Paediat & Adolescent Med, Div Paediat Pulmonol & Allergol, Graz, Austria

[24] Katholieke Univ Leuven, Dept Rehabil Sci, Leuven, Belgium

[25] Univ Hosp Gasthuisberg, Pulm Rehabil, Leuven, Belgium

[26] Queens Univ, Kingston Hlth Sci Ctr, Lab Clin Exercise Physiol, Kingston, ON, Canada

[27] Queens Univ, Kingston Hlth Sci Ctr, Resp Invest Unit, Kingston, ON, Canada

[28] UCLA, Med Ctr, Los Angeles Biomed Res Inst Harbor, Rehabil Clin Trials Ctr, Torrance, CA 90509 USA

[29] Northumbria Univ, Fac Hlth & Life Sci, Dept Sport Exercise & Rehabil, Newcastle, England

[30] Univ Hosp Wurzburg, Paediat Dept, Wurzburg, Germany

来源：

EUROPEAN RESPIRATORY REVIEW | 2019年 / 28卷 / 154期

关键词：

MAXIMAL VOLUNTARY VENTILATION; OBSTRUCTIVE PULMONARY-DISEASE; RESPIRATORY GAS-EXCHANGE; VISUAL ANALOG SCALES; HEART-RATE RECOVERY; SCIENTIFIC STATEMENT; OXYGEN-UPTAKE; PULSE-OXIMETRY; PHYSIOLOGICAL-RESPONSES; NONINVASIVE ASSESSMENT;

D O I：

10.1183/16000617.0101-2018

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The objective of this document was to standardise published cardiopulmonary exercise testing (CPET) protocols for improved interpretation in clinical settings and multicentre research projects. This document: 1) summarises the protocols and procedures used in published studies focusing on incremental CPET in chronic lung conditions; 2) presents standard incremental protocols for CPET on a stationary cycle ergometer and a treadmill; and 3) provides patients' perspectives on CPET obtained through an online survey supported by the European Lung Foundation. We systematically reviewed published studies obtained from EMBASE, Medline, Scopus, Web of Science and the Cochrane Library from inception to January 2017. Of 7914 identified studies, 595 studies with 26 523 subjects were included. The literature supports a test protocol with a resting phase lasting at least 3 min, a 3-min unloaded phase, and an 8- to 12-min incremental phase with work rate increased linearly at least every minute, followed by a recovery phase of at least 2-3 min. Patients responding to the survey (n=295) perceived CPET as highly beneficial for their diagnostic assessment and informed the Task Force consensus. Future research should focus on the individualised estimation of optimal work rate increments across different lung diseases, and the collection of robust normative data.

引用

页数：25

共 156 条

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