ent-Abietane diterpenoids from Isodon xerophilus

被引：9

作者：

Li, Li Mei ^{[2
]}

Pu, Jian Xin ^{[1
]}

Xiao, Wei Lie ^{[1
]}

Sun, Han Dong ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

[2] Chengdu Med Coll, Ctr Sci Res, Chengdu 610083, Peoples R China

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2011年 / 34卷 / 06期

关键词：

Isodon xerophilus; Lamiaceae; ent-Abietanoid; Xerophilusins XIV-XVI; RUBESCENS;

D O I：

10.1007/s12272-011-0602-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new ent-abietanoids, named xerophilusins XIV-XVI, and four known analogues, as well as four known chemical constituents were isolated from the leaves of Isodon xerophilus. Their structures were elucidated by extensive spectroscopic studies, and comparison with literature data. In addition, the cytotoxic activity of the ent-abietanoids against chronic myelogenous leukemia (K562), stomach adenocarcinoma (MKN45), and hepatocellular carcinoma (HepG2) human cell lines was investigated and no activities were observed.

引用

页码：875 / 879

页数：5

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