An efficient synthesis of trace amine-associated receptor agonist [1-14C]tyramine

被引:0
|
作者
Filer, Crist N. [1 ]
Orphanos, Demetri [1 ]
机构
[1] PerkinElmer Hlth Sci Inc, Custom Synth, Waltham, MA USA
来源
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 2019年 / 62卷 / 01期
关键词
carbon-14; trace amine; tyramine; PHARMACOLOGY;
D O I
10.1002/jlcr.3671
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The 2-step synthesis of [1-C-14]tyramine hydrochloride is described with the product being characterized by TLC, HPLC, and UV spectroscopy. Several methods are provided to purify [1-C-14]tyramine hydrochloride, and its storage and stability are also discussed.
引用
收藏
页码:24 / 27
页数:4
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