Analgesic effect of olipiphate on mouse model of chemical stimulation of peritoneum

被引：1

作者：

Zvartau, EE ^{[1
]}

Patkina, NA ^{[1
]}

Kashkin, VA ^{[1
]}

Reztsova, VV ^{[1
]}

Filov, VA ^{[1
]}

机构：

[1] IP Pavlov Med Univ, St Petersburg, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2001年 / 131卷 / 03期

关键词：

olipiphate; paracetamol; analgesic effect;

D O I：

10.1023/A:1017603516264

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We studied the analgesic effect of olipiphate, a product of lignin, against writhing provoked by intraperitoneal injection of acetic acid. Paracetamol was used as the reference drug. Both agents dose-dependently decreased the number of motor reactions caused by the irritant. Olipiphate possessed analgesic activity and efficiency comparable with those of paracetamol, but produced a more long-lasting effect.

引用

页码：254 / 256

页数：3