A miniaturized pressure independent drug delivery system for metronomic cancer therapy

被引:0
|
作者
Goldschmidtboeing, F. [1 ]
Geipel, A. [1 ]
Farhat, C. [1 ]
Jantscheff, P. [2 ]
Esser, N. [2 ]
Massing, U. [2 ]
Woias, P. [1 ]
机构
[1] Univ Freiburg, IMTEK, Dept Microsyst Engn, Lab Design Microsyst, Georges Kohler Allee 102, D-79110 Freiburg, Germany
[2] Tumor Biol Ctr, Freiburg, Germany
关键词
micropump; drug delivery; metronomic therapy;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
We present the results of our currently completed project "Active Microports". A miniaturized drug delivery system for metronomic cancer therapy was developed. It has a total weight of only 36g and is able to deliver flowrates between zero and 6 mu l/min virtually independent of the backpressure for pressures up to 30 kPa. The feasibility of the approach was demonstrated by a trial on metronomic cancer therapy with doxorubicin on a rat prostate tumor model.
引用
收藏
页码:2356 / 2359
页数:4
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