Non-Classical Structures Among Current Platinum Complexes with Potential as Antitumor Drugs

被引：15
|
作者：
Quiroga, Adoracion G. [1 ]
机构：
[1] Univ Autonoma Madrid, Dept Quim Inorgan, E-28049 Madrid, Spain
来源：
CURRENT TOPICS IN MEDICINAL CHEMISTRY | 2011年 / 11卷 / 21期
关键词：
Metallodrugs; platinum; biomolecules binding; P-ISOPROPYLBENZALDEHYDE THIOSEMICARBAZONE; ISATIN-BETA-THIOSEMICARBAZONES; INTERSTRAND CROSS-LINKS; CELL-CYCLE PROGRESSION; CYTOTOXIC ACTIVITY; IN-VITRO; TUMOR-CELLS; COORDINATION-COMPLEXES; ANTICANCER COMPLEXES; APOPTOSIS INDUCTION;
D O I：
10.2174/156802611798040723
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The potential and limitations of the non classical metallodrugs with platinum as metal are discussed in this section, focusing not only in their design but in their mechanism of action and interaction with other biomolecules to introduce and encourage the readers on the potential of this field.
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页码：2613 / 2622
页数：10
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