Immunization with a novel dc-targeting lentiviral vector induces polyfunctional cd8 t cell responses and therapeutic anti-tumor immunity

被引：0
|
作者：
Robbins, S. H. [1 ,2 ]
Clarke, B. Kelley [1 ]
Odegard, J. M. [1 ]
Tareen, S. U. [1 ]
Van Hoeven, N. [1 ]
Campbell, D. J. [1 ]
Nicholai, C. J. [1 ]
Slough, M. M. [1 ]
Vin, C. [1 ]
Baltimore, D. [2 ]
Reed, S. G. [1 ]
Dubensky, T. W., Jr. [1 ]
机构：
[1] Immune Design Corp, Seattle, WA USA
[2] CALTECH, Pasadena, CA 91125 USA
来源：
CYTOKINE | 2011年 / 56卷 / 01期
关键词：
D O I：
10.1016/j.cyto.2011.07.246
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：86 / 86
页数：1
相关论文
共 50 条
  • [21] Enforced PGC-1α expression promotes CD8 T cell persistence and anti-tumor immunity
    Dumauthioz, N.
    Tschumi, B.
    Wenes, M.
    Lopez-Mejia, I
    Fajas, L.
    Donda, A.
    Romero, P.
    Zhang, L.
    SWISS MEDICAL WEEKLY, 2018, 148 : 4S - 5S
  • [22] Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors
    Furlan, Scott N.
    Mandraju, Rajakumar
    Brewer, Travis
    Roybal, Kole
    Troutman, Ty Dale
    Hu, Wei
    Palm, Noah W.
    Unni, Arun
    Pasare, Chandrashekhar
    MABS, 2014, 6 (01) : 108 - 118
  • [23] How tumor-specific CD8 T cell activation in draining lymph nodes supports the anti-tumor CD8 T cell response
    Prokhnevska, Nataliya
    Valanparambil, Rajesh
    Jansen, Caroline
    Master, Viraj
    Sanda, Martin
    Kissick, Haydn
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [24] Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity
    Xu, Zhiguang
    Ma, Weiying
    Wang, Ji
    Chen, Haofan
    Li, Hui
    Yin, Zhinan
    Hao, Jianlei
    Chen, Kebing
    CELL REPORTS, 2024, 43 (08):
  • [25] Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity
    Xu, Zhiguang
    Ma, Weiying
    Wang, Ji
    Chen, Haofan
    Li, Hui
    Yin, Zhinan
    Hao, Jianlei
    Chen, Kebing
    CELL REPORTS, 2024, 43 (10):
  • [26] YTHDF2 upregulation and subcellular localization dictate CD8 T cell polyfunctionality in anti-tumor immunity
    Zhang, Haiyan
    Luo, Xiaojing
    Yang, Wei
    Wu, Zhiying
    Zhao, Zhicong
    Pei, Xin
    Zhang, Xue
    Chen, Chonghao
    Lei, Josh Haipeng
    Shi, Qingxia
    Zhao, Qi
    Chen, Yanxing
    Wu, Wenwei
    Zeng, Zhaolei
    Ju, Huai-Qiang
    Qiu, Miaozhen
    Liu, Jun
    Shen, Bin
    Chen, Minshan
    Chen, Jianjun
    Deng, Chu-Xia
    Xu, Rui-Hua
    Hou, Jiajie
    NATURE COMMUNICATIONS, 2024, 15 (01)
  • [27] CONTROL OF ANTI-TUMOR CD8+ T-CELL RESPONSES
    Morgan, David J.
    ANTICANCER RESEARCH, 2008, 28 (5C) : 3413 - 3413
  • [28] Intratumoral expression of IL12 using the ZVex® dendritic cell-targeting lentiviral vector exerts potent anti-tumor effects via induction of multiple immune effectors, including CD8 T cell responses
    Albershardt, Tina C.
    Leleux, Jardin
    Reeves, Rebecca S.
    ter Meulen, Jan
    Berglund, Peter
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2017, 5
  • [29] YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response
    Lebid, Andriana
    Chung, Liam
    Pardoll, Drew M.
    Pan, Fan
    FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [30] Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine
    Karan, Dev
    Krieg, Arthur M.
    Lubaroff, David M.
    INTERNATIONAL JOURNAL OF CANCER, 2007, 121 (07) : 1520 - 1528
12345