Neuroimaging of tuberous sclerosis: Spectrum of Pathologic findings and frontiers in imaging

被引：54

作者：

Kalantari, Babak N. ^{[1
]}

Salamon, Noriko ^{[1
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Radiol, Los Angeles, CA 90095 USA

来源：

AMERICAN JOURNAL OF ROENTGENOLOGY | 2008年 / 190卷 / 05期

关键词：

FDG PET; fusion imaging; magnetoencephalography; MRI; pediatric radiology; tuberous sclerosis;

D O I：

10.2214/AJR.07.2928

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

OBJECTIVE. The purpose of this article is to present neuroimaging findings in tuberous sclerosis complex, including recently developed imaging techniques that have demonstrated clinical benefit to this patient population. CONCLUSION. Neuroimaging advances have improved the diagnosis of tuberous sclerosis complex and the treatment of children with this condition. Superimposition of functional information from PET onto MRI allows accurate and noninvasive identification of epileptogenic tubers, improving surgical cure rates. Magnetic source imaging can also be used to localize epileptiform activity arising from tubers.

引用

页码：W304 / W309

页数：6

共 15 条

[1] MR IMAGING OF TUBEROUS SCLEROSIS - PATHOGENESIS OF THIS PHAKOMATOSIS, USE OF GADOPENTETATE DIMEGLUMINE, AND LITERATURE-REVIEW [J].

BRAFFMAN, BH ;

BILANIUK, LT ;

NAIDICH, TP ;

ALTMAN, NR ;

POST, MJD ;

QUENCER, RM ;

ZIMMERMAN, RA ;

BRODY, BA .

RADIOLOGY, 1992, 183 (01) :227-238

[2] Infantile spasm-associated microencephaly in tuberous sclerosis complex and cortical dysplasia [J].

Chandra, P. S. ;

Salamon, N. ;

Nguyen, S. T. ;

Chang, J. W. ;

Huynh, M. N. ;

Cepeda, C. ;

Leite, J. P. ;

Neder, L. ;

Koh, S. ;

Vinters, H. V. ;

Mathern, G. W. .

NEUROLOGY, 2007, 68 (06) :438-445

[3] FDG-PET/MRI coregistration and diffusion-tensor imaging distinguish epileptogenic tubers and cortex in patients with tuberous sclerosis complex: A preliminary report [J].

Chandra, Poodipedi S. ;

Salamon, Noriko ;

Huang, Jimmy ;

Wu, Joyce Y. ;

Koh, Susan ;

Vinters, Harry V. ;

Mathern, Gary W. .

EPILEPSIA, 2006, 47 (09) :1543-1549

[4]

Chugani Harry T, 2005, Epilepsy Curr, V5, P201, DOI 10.1111/j.1535-7511.2005.00064.x

[5] Intractable seizures in tuberous sclerosis complex: From molecular pathogenesis to the rationale for treatment [J].

Curatolo, P ;

Bombardieri, R ;

Verdecchia, M ;

Seri, S .

JOURNAL OF CHILD NEUROLOGY, 2005, 20 (04) :318-325

[6]

DIPAOLO D, 1995, AM J NEURORADIOL, V16, P1360

[7] Rapamycin causes regression of astrocytomas in tuberous sclerosis complex [J].

Franz, DN ;

Leonard, J ;

Tudor, C ;

Chuck, G ;

Care, M ;

Sethuraman, G ;

Dinopoulos, A ;

Thomas, G ;

Crone, KR .

ANNALS OF NEUROLOGY, 2006, 59 (03) :490-498

[8] Increased brain apparent diffusion coefficient in tuberous sclerosis [J].

Garaci, FG ;

Floris, R ;

Bozzao, A ;

Manenti, G ;

Simonetti, A ;

Lupattelli, T ;

Curatolo, P ;

Simonetti, G .

RADIOLOGY, 2004, 232 (02) :461-465

[9] Magnetization transfer in the investigation of patients with tuberous sclerosis [J].

Girard, N ;

Zimmerman, RA ;

Schnur, RE ;

Haselgrove, J ;

Christensen, K .

NEURORADIOLOGY, 1997, 39 (07) :523-528

[10]

Griffiths PD, 1998, ACTA RADIOL, V39, P482

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