Metformin inhibits prostate cancer growth induced by a high-fat diet in Pten-deficient model mice

被引：15
作者：
Hayashi, Takuji [1 ]
Fujita, Kazutoshi [1 ]
Matsushita, Makoto [1 ]
Hayashi, Yujiro [1 ]
Uemura, Motohide [1 ,2 ]
Nonomura, Norio [1 ]
机构：
[1] Osaka Univ, Grad Sch Med, Dept Urol, Suita, Osaka, Japan
[2] Osaka Univ, Grad Sch Med, Dept Therapeut Urol Oncol, Suita, Osaka, Japan
来源：
INTERNATIONAL JOURNAL OF UROLOGY | 2019年 / 26卷 / 02期
关键词：
metformin; prostate cancer; high-fat diet; model mice;
D O I：
10.1111/iju.13847
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：307 / 309
页数：3
相关论文
共 7 条
  • [1] High-Fat Diet-Induced Inflammation Accelerates Prostate Cancer Growth via IL6 Signaling
    Hayashi, Takuji
    Fujita, Kazutoshi
    Nojima, Satoshi
    Hayashi, Yujiro
    Nakano, Kosuke
    Ishizuya, Yu
    Wang, Cong
    Yamamoto, Yoshiyuki
    Kinouchi, Toshiro
    Matsuzaki, Kyosuke
    Jingushi, Kentaro
    Kato, Taigo
    Kawashima, Atsunari
    Nagahara, Akira
    Ujike, Takeshi
    Uemura, Motohide
    Pena, Maria Del Carmen Rodriguez
    Gordetsky, Jennifer B.
    Morii, Eiichi
    Tsujikawa, Kazutake
    Netto, George J.
    Nonomura, Norio
    [J]. CLINICAL CANCER RESEARCH, 2018, 24 (17) : 4309 - 4318
  • [2] PIGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity
    Incio, Joao
    Tam, Josh
    Rahbari, Nuh N.
    Suboj, Priya
    McManus, Dan T.
    Chin, Shan M.
    Vardam, Trupti D.
    Batista, Ana
    Babykutty, Suboj
    Jung, Keehoon
    Khachatryan, Anna
    Hato, Tai
    Ligibel, Jennifer A.
    Krop, Ian E.
    Puchner, Stefan B.
    Schlett, Christopher L.
    Hoffmman, Udo
    Ancukiewicz, Marek
    Shibuya, Masabumi
    Carmeliet, Peter
    Soares, Raquel
    Duda, Dan G.
    Jain, Rakesh K.
    Fukumura, Dai
    [J]. CLINICAL CANCER RESEARCH, 2016, 22 (12) : 2993 - 3004
  • [3] Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory Infiltration
    Liu, Qiuli
    Tong, Dali
    Liu, Gaolei
    Gao, Jie
    Wang, Lin-ang
    Xu, Jing
    Yang, Xingxia
    Xie, Qiubo
    Huang, Yiqiang
    Pang, Jian
    Wang, Luofu
    He, Yong
    Zhang, Dianzheng
    Ma, Qiang
    Lan, Weihua
    Jiang, Jun
    [J]. CLINICAL CANCER RESEARCH, 2018, 24 (22) : 5622 - 5634
  • [4] Metformin Use is Associated with Improved Survival for Patients with Advanced Prostate Cancer on Androgen Deprivation Therapy
    Richards, Kyle A.
    Liou, Jinn-ing
    Cryns, Vincent L.
    Downs, Tracy M.
    Abel, E. Jason
    Jarrard, David F.
    [J]. JOURNAL OF UROLOGY, 2018, 200 (06) : 1256 - 1262
  • [5] Metformin Reduces Prostate Tumor Growth, in a Diet-Dependent Manner, by Modulating Multiple Signaling Pathways
    Sarmento-Cabral, Andre
    L-Lopez, Fernando
    Gahete, Manuel D.
    Castano, Justo P.
    Luque, Raul M.
    [J]. MOLECULAR CANCER RESEARCH, 2017, 15 (07) : 862 - 874
  • [6] Xiao Y, 2017, ONCOTARGET, V59
  • [7] Metformin: A Bridge between Diabetes and Prostate Cancer
    Zingales, Veronica
    Distefano, Alfio
    Raffaele, Marco
    Zanghi, Antonio
    Barbagallo, Ignazio
    Vanella, Luca
    [J]. FRONTIERS IN ONCOLOGY, 2017, 7
1