The Database of Interacting Proteins: 2004 update

被引:1517
作者
Salwinski, L
Miller, CS
Smith, AJ
Pettit, FK
Bowie, JU
Eisenberg, D
机构
[1] Univ Calif Los Angeles, Howard Hughes Med Inst, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, UCLA DOE Inst Genom & Proteom, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, Inst Mol Biol, Dept Biol Chem, Los Angeles, CA 90095 USA
关键词
D O I
10.1093/nar/gkh086
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Database of Interacting Proteins (http://dip.doe-mbi.ucla.edu) aims to integrate the diverse body of experimental evidence on protein-protein interactions into a single, easily accessible online database. Because the reliability of experimental evidence varies widely, methods of quality assessment have been developed and utilized to identify the most reliable subset of the interactions. This CORE set can be used as a reference when evaluating the reliability of high-throughput protein-protein interaction data sets, for development of prediction methods, as well as in the studies of the properties of protein interaction networks.
引用
收藏
页码:D449 / D451
页数:3
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