Physiology of cardiac pacing in children: The importance of the ventricular pacing site

被引：20
作者：
Vanagt, Ward Y. [1 ]
Prinzen, Frits W. [1 ]
Delhaas, Tammo [2 ]
机构：
[1] Maastricht Univ, Dept Physiol, Cardiovasc Res Inst, NL-6200 MD Maastricht, Netherlands
[2] Univ Limburg, Cardiovasc Res Inst, Dept Pediat, NL-6200 MD Maastricht, Netherlands
来源：
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY | 2008年 / 31卷
关键词：
pacing; pediatrics; dyssynchrony; ventricular;
D O I：
10.1111/j.1540-8159.2008.00950.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Children with congenital or acquired atrioventricular block are provided with ventricular rate support from a pacing lead that traditionally is positioned at the right ventricular (RV) apex. However, RV apical pacing causes dyssynchronous electrical activation and left ventricular (LV) contraction, resulting in decreased LV function. Chronic RV apical pacing leads to deterioration of LV function and morphology, resulting in cardiac failure in approximately 7% of children. This review describes the pathophysiology of pacing-induced dyssynchronous LV activation and contraction, especially as a result of chronic RV apical pacing. Furthermore, this review provides an overview of the possible alternative pacing sites, such as the RV outflow tract, His-bundle, LV apex, and biventricular pacing.
引用
收藏
页码：S24 / S27
页数：4
相关论文
共 15 条
[1]  
Blanc JJ, 1997, CIRCULATION, V96, P3273
[2]   Comparison of the haemodynamic effects of right ventricular outflow-tract pacing with right ventricular apex pacing - A quantitative review [J].
de Cock, CC ;
Giudici, MC ;
Twisk, JV .
EUROPACE, 2003, 5 (03) :275-278
[3]   Permanent, direct his-bundle pacing - A novel approach to cardiac pacing in patients with normal His-purkinje activation [J].
Deshmukh, P ;
Casavant, DA ;
Romanyshyn, M ;
Anderson, K .
CIRCULATION, 2000, 101 (08) :869-877
[4]   Resynchronization therapy in pediatric and congenital heart disease patients - An international multicenter study [J].
Dubin, AM ;
Janousek, J ;
Rhee, E ;
Strieper, MJ ;
Cecchin, F ;
Law, IH ;
Shannon, KM ;
Temple, J ;
Rosenthal, E ;
Zimmerman, FJ ;
Davis, A ;
Karpawich, PP ;
Al Ahmad, A ;
Vetter, VL ;
Kertesz, NJ ;
Shah, M ;
Snyder, C ;
Stephenson, E ;
Emmel, M ;
Sanatani, S ;
Kanter, R ;
Batra, A ;
Collins, KK .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 46 (12) :2277-2283
[5]   Resynchronization pacing is a useful adjunct to the management of acute heart failure after surgery for congenital heart defects [J].
Janousek, J ;
Vojtovic, P ;
Hucín, B ;
Tláskal, T ;
Gebauer, RA ;
Gebauer, R ;
Matejka, T ;
Marek, J ;
Reich, O .
AMERICAN JOURNAL OF CARDIOLOGY, 2001, 88 (02) :145-152
[6]   Chronic right ventricular pacing and cardiac performance: The pediatric perspective [J].
Karpawich, PP .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2004, 27 (06) :844-849
[7]   Dilated cardiomyopathy following right ventricular pacing for AV block in young patients: Resolution after upgrading to biventricular pacing systems [J].
Moak, Jeffrey P. ;
Hasbani, Keren ;
Ramwell, Carolyn ;
Freedenberg, Vicki ;
Berger, John T. ;
Dirusso, Gregory ;
Callahan, Patrick .
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2006, 17 (10) :1068-1071
[8]   Left ventricular septal and apex pacing for optimal pump function in canine hearts [J].
Peschar, M ;
de Swart, H ;
Michels, KJ ;
Reneman, RS ;
Prinzen, FW .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 41 (07) :1218-1226
[9]   Relation between the pacing induced sequence of activation and left ventricular pump function in animals [J].
Prinzen, FW ;
Peschar, M .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2002, 25 (04) :484-498
[10]   Electromechanical coupling, uncoupling, and ventricular function in patients with bundle branch block:: A tissue-doppler echocardiographic study [J].
Quintana, M ;
Saha, S ;
Rohani, M ;
del Furia, F ;
Roumina, S ;
Lind, B ;
Hayashi, S ;
Brodin, LÅ .
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, 2004, 21 (08) :687-698
12