Risk Factors and Outcome of Seizures After Chronic Subdural Hematoma

被引：33

作者：

Huang, Yu-Hua ^{[1
]}

Yang, Tzu-Ming ^{[1
]}

Lin, Yu-Jun ^{[1
]}

Tsai, Nai-Wen ^{[2
]}

Lin, Wei-Che ^{[3
]}

Wang, Hung-Chen ^{[1
]}

Chang, Wen-Neng ^{[2
]}

Lu, Cheng-Hsien ^{[2
,4
]}

机构：

[1] Chang Gung Univ, Coll Med, Kaohsiung Med Ctr, Dept Neurosurg,Chang Gung Mem Hosp, Kaohsiung, Taiwan

[2] Chang Gung Univ, Coll Med, Dept Neurol, Chang Gung Mem Hosp,Kaohsiung Med Ctr, Kaohsiung Hsien, Taiwan

[3] Chang Gung Univ, Dept Radiol, Coll Med, Chang Gung Mem Hosp,Kaohsiung Med Ctr, Kaohsiung, Taiwan

[4] Natl Sun Yat Sen Univ, Dept Biol Sci, Kaohsiung 80424, Taiwan

来源：

NEUROCRITICAL CARE | 2011年 / 14卷 / 02期

关键词：

Chronic subdural hematoma; Outcome; Risk factors; Seizure; COMPUTERIZED-TOMOGRAPHY; CLINICAL ARTICLE; RECURRENCE; DRAINAGE;

D O I：

10.1007/s12028-011-9509-8

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Seizures are important neurologic complications of chronic subdural hematoma (CSDH). A better understanding of risk factors of seizures following CSDH is needed to identify the patient who will require treatment. This one-year retrospective study enrolled 100 adult CSDH patients. Baseline prognostic variables were analyzed by Cox's proportional hazards model after a minimum of 18 months of follow-up. Seizures occurred in 11 CSDH patients, including acute symptomatic seizures in 6.0% (6/100) and unprovoked seizures in 5.0% (5/100). None progressed to status epilepticus during hospitalization. After a minimum of 18 months of follow-up, the mean Glasgow Outcome Scores (GOSs) were 4.1 +/- A 1.4 and 4.7 +/- A 0.7 for patients with and without seizures, respectively. Cox's proportional hazards model showed that only the mean GCS on admission (P = 0.004, OR = 0.78, 95% CI = 0.67-0.93) was independently associated with seizures, and a decrease of one mean GCS increased the seizure rate by 21.6%. Lower mean GCS on admission is independently predictive of seizures, most of which occur within the first three months after CSDH.

引用

页码：253 / 259

页数：7

共 22 条

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