Tract-Based Spatial Statistics Analysis of Diffusion-Tensor Imaging Data in Patients with Small Cell Lung Cancer.

被引：0
作者：
Benezi, S. [1 ,2 ]
Karavasilis, E. [3 ]
Karanasiou, I. S. [1 ]
Matsopoulos, G. [1 ]
Ventouras, E. [4 ]
Uzunoglu, N. [1 ]
Kouloulias, V [5 ]
Papathanasiou, M. [5 ]
Foteineas, A. [5 ]
Soldatos, Th [3 ]
Iosif, Ch [3 ]
Efstathopoulos, E. [5 ]
Kelekis, N. [5 ]
Kelekis, D. [3 ]
机构：
[1] Natl Tech Univ Athens, Sch Elect & Comp Engn, Microwave & Fiber Opt Lab, GR-10682 Athens, Greece
[2] Univ Patras, Sch Med, GR-26110 Patras, Greece
[3] Evgenidion Gen Hosp, Res Ctr Radiol & Imaging, Athens, Greece
[4] Technol Educ Inst Athens, Dept Med Instrumentat Technol, Athens, Greece
[5] Univ Athens, Div Radiol Radiotherapy 2, Athens, Greece
来源：
2014 EAI 4TH INTERNATIONAL CONFERENCE ON WIRELESS MOBILE COMMUNICATION AND HEALTHCARE (MOBIHEALTH) | 2014年
关键词：
component; Diffusion Tensor Imaging; DTI; Tract-Based Spatial Statistics; TBSS; Small Cell Lung Cancer; SCLC; Prophylactic Cranial Irradiation; PCI; Fractional Anisotropy; FA; PROPHYLACTIC CRANIAL IRRADIATION; RADIATION-INDUCED CHANGES; WHITE-MATTER;
D O I：
10.4108/icst.mobihealth.2014.257513
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Prophylactic cranial irradiation (PCI) is known to improve survival to a significant degree in Small Cell Lung Cancer (SCLC) patients. The aim of our study is to investigate changes in structural connectivity between healthy-volunteers and patients with SCLC, before and after PCI treatment. In this preliminary study we use diffusion tensor imaging (DTI) to identify changes in white matter structure in patient group pre radiotherapy to control group. The results have showed alterations in white matter structure. In the patient group lower fractional anisotropy (FA) and higher eigenvalues in white matter regions are observed compared to the control group. The results presented herein are subject to further investigation with larger patient and control groups.
引用
收藏
页码：99 / 102
页数：4
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