Soil-Transmitted Helminths of Humans in Southeast Asia-Towards Integrated Control

被引:50
作者
Jex, Aaron R. [1 ]
Lim, Yvonne A. L. [2 ]
Bethony, Jeffrey M. [3 ]
Hotez, Peter J. [3 ]
Young, Neil D. [1 ]
Gasser, Robin B. [1 ]
机构
[1] Univ Melbourne, Dept Vet Sci, Werribee, Vic 3030, Australia
[2] Univ Malaya, Fac Med, Dept Parasitol, Kuala Lumpur, Malaysia
[3] George Washington Univ, Med Ctr, Dept Microbiol Immunol & Trop Med, Washington, DC 20037 USA
来源
ADVANCES IN PARASITOLOGY, VOL 74 | 2011年 / 74卷
关键词
INTESTINAL PARASITIC INFECTIONS; C-OXIDASE SUBUNIT-1; SCHOOL DEWORMING PROGRAM; ASSURANCE SAMPLING LQAS; NECATOR-AMERICANUS; OESOPHAGOSTOMUM-BIFURCUM; NUTRITIONAL-STATUS; RIBOSOMAL DNA; STRONGYLOIDES-STERCORALIS; ITS1-5.8S-ITS2; SEGMENT;
D O I
10.1016/B978-0-12-385897-9.00004-5
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Soil-transmitted helminths (STHs) pose significant public health challenges in many countries of Southeast Asia (SEA). Overall, approximately one-third of the world's cases of ascariasis, trichuriasis, and hookworm disease occur in the 11 major SEA countries. Various countries are at different stages in their response to controlling these diseases. For instance, in Malaysia and Thailand, the major burden of disease is confined to rural/remote, indigenous and/or refugee populations. In countries, such as Cambodia, Lao People's Democratic Republic and Vietnam, the burden remains high, although extensive deworming programmes are underway and are yielding encouraging results. The present chapter reviews the current status of 5TH infections in SEA, identifies knowledge gaps and offers a perspective on the development of improved, integrated surveillance and control in this geographical region. It indicates that advances in our understanding of the epidemiology of these parasites, through the strategic use of molecular and predictive (e.g. geographical information systems (GIS) and remote sensing (RS)) technologies, could readily underpin future research and control programmes. It is hoped that the gradual move towards integrated treatment/control programmes will assist substantially in decreasing the chronic disease burden linked to STHs, thus increasing human health and welfare, and supporting socioeconomic growth and development in SEA countries.
引用
收藏
页码:231 / 265
页数:35
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