Microdialysis of salicylic acid from viscous emulsion samples prior to high-performance liquid chromatographic determination

被引：15

作者：

Jen, JF ^{[1
]}

Tsai, YY

Yang, TC

机构：

[1] Natl Chung Hsing Univ, Dept Chem, Taichung 40217, Taiwan

[2] Natl Kaohsiung Normal Univ, Dept Chem, Kaohsiung, Taiwan

来源：

JOURNAL OF CHROMATOGRAPHY A | 2001年 / 912卷 / 01期

关键词：

microdialysis; salicylic acid;

D O I：

10.1016/S0021-9673(01)00562-3

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A micro-dialysis method was developed to isolate aqueous salicylic acid from viscous emulsion samples prior to HPLC determination. The optimal conditions for obtaining dialysis efficiency of salicylic acid as well as chromatographic conditions were investigated. Experimental results indicated that the dialysis achieved at pH 2.0 (0.025 M phosphate solution), 0.5 M NaCl addition, and 50-mul/min flow-rate of perfusion stream offered an optimal result. The proposed method provided a simple procedure for isolating salicylic acid from viscous emulsion samples. Application was illustrated by the analysis of salicylic acid in cosmetic products. (C) 2001 Elsevier Science BN. All rights reserved.

引用

页码：39 / 43

页数：5

共 22 条

[1] Direct analysis of food samples by high-performance liquid chromatography [J].

Bovanová, L ;

Brandsteterová, E .

JOURNAL OF CHROMATOGRAPHY A, 2000, 880 (1-2) :149-168

[2] Rapid on-line microdialysis hyphenated technique for the dynamic monitoring of extracellular pyruvate, lactic acid and ascorbic acid during cerebral ischemia [J].

Cheng, FC ;

Yang, DY ;

Wu, TF ;

Chen, SH .

JOURNAL OF CHROMATOGRAPHY B, 1999, 723 (1-2) :31-38

[3] Determination of flumequine and oxolinic acid in fortified chicken tissue using on-line dialysis and high-performance liquid chromatography with fluorescence detection [J].

Eng, GY ;

Maxwell, RJ ;

Cohen, E ;

Piotrowski, EG ;

Fiddler, W .

JOURNAL OF CHROMATOGRAPHY A, 1998, 799 (1-2) :349-354

[4] THE DETERMINATION OF SUGARS IN BEVERAGES AND MEDICINES USING ONLINE DIALYSIS FOR SAMPLE PREPARATION [J].

GREENWAY, GM ;

KOMETA, N .

FOOD CHEMISTRY, 1995, 53 (01) :105-110

[5] Fully automated precolumn derivatization, on-line dialysis and high-performance liquid chromatographic analysis of amino acids in food, beverages and feedstuff [J].

Heems, D ;

Luck, G ;

Fraudeau, C ;

Vérette, E .

JOURNAL OF CHROMATOGRAPHY A, 1998, 798 (1-2) :9-17

[6] Determination of hydroxyl radicals in an advanced oxidation process with salicylic acid trapping and liquid chromatography [J].

Jen, JF ;

Leu, MF ;

Yang, TC .

JOURNAL OF CHROMATOGRAPHY A, 1998, 796 (02) :283-288

[7] Automated on-line dialysis, trace enrichment and high-performance liquid chromatography Inhibition of interaction with the dialysis membrane and disruption of protein binding in the determination of clozapine in human plasma [J].

Johansen, K ;

Krogh, M ;

Rasmussen, KE .

JOURNAL OF CHROMATOGRAPHY B, 1997, 690 (1-2) :223-231

[8] On-line dialysis coupled to a capillary electrophoresis system for determination of small anions [J].

Kuban, P ;

Karlberg, B .

ANALYTICAL CHEMISTRY, 1997, 69 (06) :1169-1173

[9] Membrane surface characterisation by contact angle measurements using the immersed method [J].

Rosa, MJ ;

dePinho, MN .

JOURNAL OF MEMBRANE SCIENCE, 1997, 131 (1-2) :167-180

[10] Automated on-line dialysis and liquid chromatography of methylenedioxylated amphetamines in plasma and serum samples [J].

Sadeghipour, F ;

Veuthey, JL .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1998, 17 (4-5) :801-810

← 1 2 3 →