Synthesis of new derivatives of 1-(3-aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid

被引：7

作者：

Kasimogullari, Rahmi ^{[1
]}

Zengin, Belma ^{[1
]}

Maden, Makbule ^{[1
]}

Mert, Samet ^{[1
]}

Kazaz, Cavit ^{[2
]}

机构：

[1] Dumlupinar Univ, Dept Chem, Art & Sci Fac, Kutahya, Turkey

[2] Ataturk Univ, Dept Chem, Fac Sci, Erzurum, Turkey

来源：

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY | 2010年 / 75卷 / 12期

关键词：

pyrazole-3-carboxylic acid; pyridazin; diazonium salts; cyclocondensation; AZO-HYDRAZONE TAUTOMERISM; N-15;

D O I：

10.2298/JSC101018135K

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1-(3-Aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid (1) was synthesized according to the literature.(1) 2-(3-Aminophenyl)-2,6-dihydro-3,4-diphenyl-7H-pyrazolo[3,4-d]pyridazin-7-one (5) was obtained by the cyclocondensation reaction of 1 with hydrazine hydrate. New pyrazole derivatives of compounds 1 and 5 were synthesized by their reaction with beta-diketones, beta-ketoesters, beta-naphthol, phenol and various other reagents. The structures of the synthesized compounds were characterized by H-1-NMR, C-13-NMR, IR and mass spectroscopy, as well as elemental analysis.

引用

页码：1625 / 1635

页数：11

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