Neuroimaging in posttraumatic stress disorder and other stress-related disorders

被引：135
作者：
Bremner, J. Douglas
机构：
[1] Emory Univ, Atlanta, GA 30306 USA
[2] Emory Univ, Sch Med, Dept Psychiat & Behav Sci, Atlanta, GA 30306 USA
[3] Emory Univ Hosp, Sch Med, Dept Radiol, Atlanta, GA 30322 USA
来源：
NEUROIMAGING CLINICS OF NORTH AMERICA | 2007年 / 17卷 / 04期
关键词：
D O I：
10.1016/j.nic.2007.07.003
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Traumatic stress has a broad range of effects on the brain. Brain areas implicated in the stress response include the amygdala, the hippocampus, and the prefrontal cortex. Studies in patients who have posttraumatic stress disorder (PTSD) and other psychiatric disorders related to stress have replicated findings in animal studies by finding alterations in these brain areas. Brain regions implicated in PTSD also play an important role in memory function, highlighting the important interplay between memory and the traumatic stress response. Abnormalities in these brain areas are hypothesized to underlie symptoms of PTSD and other stress-related psychiatric disorders.
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收藏
页码：523 / +
页数：17
相关论文
共 162 条
[71]  
Jenkins MA, 1998, AM J PSYCHIAT, V155, P278
[72]   Positron emission tomography in female patients with Borderline personality disorder [J].
Juengling, FD ;
Schmahl, C ;
Hesslinger, B ;
Ebert, D ;
Bremner, JD ;
Gostomzyk, J ;
Bohus, M ;
Lieb, K .
JOURNAL OF PSYCHIATRIC RESEARCH, 2003, 37 (02) :109-115
[73]   POSTTRAUMATIC-STRESS-DISORDER IN THE NATIONAL COMORBIDITY SURVEY [J].
KESSLER, RC ;
SONNEGA, A ;
BROMET, E ;
HUGHES, M ;
NELSON, CB .
ARCHIVES OF GENERAL PSYCHIATRY, 1995, 52 (12) :1048-1060
[74]   Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: A meta-analysis [J].
Kitayama, N ;
Vaccarino, V ;
Kutner, M ;
Weiss, P ;
Bremner, JD .
JOURNAL OF AFFECTIVE DISORDERS, 2005, 88 (01) :79-86
[75]   Reduced glucose metabolism in temporo-parietal cortices of women with borderline personality disorder [J].
Lange, C ;
Kracht, L ;
Herholz, K ;
Sachsse, U ;
Irle, E .
PSYCHIATRY RESEARCH-NEUROIMAGING, 2005, 139 (02) :115-126
[76]   Recall of emotional states in posttraumatic stress disorder: An fMRI investigation [J].
Lanius, RA ;
Williamson, PC ;
Hopper, J ;
Densmore, M ;
Boksman, K ;
Gupta, MA ;
Neufeld, RWJ ;
Gati, JS ;
Menon, RS .
BIOLOGICAL PSYCHIATRY, 2003, 53 (03) :204-210
[77]   Neural correlates of traumatic memories in posttraumatic stress disorder: A functional MRI investigation [J].
Lanius, RA ;
Williamson, PC ;
Densmore, M ;
Boksman, K ;
Gupta, MA ;
Neufeld, RW ;
Gati, JS ;
Menon, RS .
AMERICAN JOURNAL OF PSYCHIATRY, 2001, 158 (11) :1920-1922
[78]   Magnetic resonance imaging a magnetic resonance spectroscopy study of deficits in hippocampal structure in fire victims with recent-onset posttraumatic stress disorder [J].
Li, Lingjiang ;
Chen, Shulin ;
Liu, Jun ;
Zhang, Jinli ;
He, Zhong ;
Lin, Xu .
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 2006, 51 (07) :431-437
[79]   Brain activation in PTSD in response to trauma-related stimuli [J].
Liberzon, I ;
Taylor, SF ;
Amdur, R ;
Jung, TD ;
Chamberlain, KR ;
Minoshima, S ;
Koeppe, RA ;
Fig, LM .
BIOLOGICAL PSYCHIATRY, 1999, 45 (07) :817-826
[80]   Neural correlates of traumatic recall in posttraumatic stress disorder [J].
Liberzon, I ;
Britton, JC ;
Phan, KL .
STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS, 2003, 6 (03) :151-156
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