Retrieval and Investigation of Data on SARS-CoV-2 and COVID-19 Using Bioinformatics Approach

被引：24

作者：

Fahmi, Muhamad ^{[1
,2
]}

Kharisma, Viol Dhea ^{[3
,4
,5
]}

Ansori, Arif Nur Muhammad ^{[6
,7
]}

Ito, Masahiro ^{[1
,2
]}

机构：

[1] Ritsumeikan Univ, Grad Sch Life Sci, Adv Life Sci Program, Shiga, Japan

[2] Universal Sci Educ & Res Network USERN, Systemat Review & Metaanal Expert Grp SRMEG, Kusatsu, Japan

[3] Brawijaya Univ, Fac Mathemat & Nat Sci, Dept Biol, Master Program Biol, Malang, Indonesia

[4] Generasi Biol Indonesia GENBINESIA Fdn, Div Mol Biol & Genet, Computat Virol & Complex Sci Res Unit, Gresik, Indonesia

[5] Universal Sci Educ & Res Network USERN, Systemat Review & Metaanal Expert Grp SRMEG, Malang, Indonesia

[6] Airlangga Univ, Fac Vet Med, Doctoral Program Vet Sci, Kampus C Univ Airlangga, Surabaya, Indonesia

[7] Universal Sci Educ & Res Network USERN, Systemat Review & Metaanal Expert Grp SRMEG, Surabaya, Indonesia

来源：

CORONAVIRUS DISEASE - COVID-19 | 2021年 / 1318卷

关键词：

COVID-19; Databases; Information hubs; Molecular evolution; Phylogenetic inference; SARS-CoV-2; Vaccine design; MULTIPLE SEQUENCE ALIGNMENT; HEPATITIS-C VIRUS; B-CELL EPITOPES; DATA-BANK PDB; HLA-DR; CORONAVIRUS; PREDICTION; PROTEIN; RECOMBINATION; MECHANISMS;

D O I：

10.1007/978-3-030-63761-3_47

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Sudden emergence and a rapid outbreak of SARS-CoV-2 accompanied by a devastating impact on the economy and public health has driven extensive scientific mobilization to study and elucidate the various associated concerns about SARS-CoV-2. Bioinformatics plays a crucial role in addressing and providing solutions to questions about SARS-CoV-2. It helps shorten the duration for the vaccine development process and the discovery of potential clinical interventions through the simulation and information retrieval, and the development of well-ordered information hubs and resources, which are essential to derive data and meaningful findings from the current massive information about SARS-CoV-2. Advanced algorithms in this field also provide approaches that are essential to elucidate the relationship, origin, and evolutionary process of SARS-CoV-2. Here, we report essential bioinformatics entities, such as database and platform development, molecular evolution and phylogenetic analyses, and vaccine designs, that are useful to solve the SARS-CoV-2 conundrum.

引用

页码：839 / 857

页数：19

共 107 条

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