Competition for cytokines:: Treg cells take all

被引：75

作者：

Scheffold, Alexander ^{[1
]}

Murphy, Kenneth M.

Hoefer, Thomas

机构：

[1] Deutsch Rheumaforsch Zentrum Berlin, D-10115 Berlin, Germany

[2] Washington Univ, Sch Med, Howard Hughes Med Inst, Dept Pathol, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Howard Hughes Med Inst, Ctr Immunol, St Louis, MO 63110 USA

[4] German Canc Res Ctr, Bioquantzentrum, D-69120 Heidelberg, Germany

来源：

NATURE IMMUNOLOGY | 2007年 / 8卷 / 12期

关键词：

D O I：

10.1038/ni1207-1285

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Thymus-derived regulatory T cells are thought to suppress target cells by either a cell contact-dependent mechanism or the production of inhibitory cytokines. A new study suggests a third strategy of apoptosis induced by the consumption of interleukin 2 and other T cell growth factors by regulatory T cells.

引用

页码：1285 / 1287

页数：4

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