Formal synthesis of the piperidine alkaloid (±)-prosophylline using polymer-supported dihydro-2H-pyridin-3-one

被引：9

作者：

Couladouros, Elias A. ^{[1
,2
]}

Strongilos, Alexandros T. ^{[1
]}

Neokosmidis, E. ^{[1
,2
]}

机构：

[1] Agr Univ Athens, Chem Labs, Athens 11855, Greece

[2] NCSR Demokritos, Inst Phys Chem, Nat Prod Synth & Bioorgan Chem Lab, GR-15310 Athens, Greece

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 46期

关键词：

solid-phase synthesis; piperidine alkaloids; natural products; polymorphic scaffolds;

D O I：

10.1016/j.tetlet.2007.09.075

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of polymer-supported 2,6-disubstituted-dihydro-2H-pyridin-3-one, as the 'polymorphic' core molecule for the formal synthesis of the piperidine alkaloid (+/-)-prosophylline is presented. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：8227 / 8229

页数：3

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