Monte Carlo dosimetric evaluation in PET exams for patients with different BMI and heights

被引:0
作者
Belinato, Walmir [1 ,2 ]
Silva, Rogerio M. V. [3 ]
Perini, Ana P. [1 ,4 ,5 ,6 ]
Neves, Lucio P. [1 ,4 ,6 ]
Santos, Carla J. [1 ,6 ]
Souza, Divanizia N. [7 ]
Santos, William S. [1 ,4 ]
机构
[1] Ionizing Radiat Dosimetry Med Grp, Rio De Janeiro, Brazil
[2] Inst Fed Educ Ciencia & Tecnol Bahia, Dept Ensino, Vitoria Da Conquista, BA, Brazil
[3] Inst Canc Ceara, Fortaleza, CE, Brazil
[4] Univ Fed Uberlandia, Inst Fis, Uberlandia, MG, Brazil
[5] CNEN, SP, IPEN, Sao Paulo, SP, Brazil
[6] Univ Fed Uberlandia, Fac Engn Elect, Programa Posgrad Engn Biomed, Uberlandia, MG, Brazil
[7] Univ Fed Sergipe, Dept Fis, Sao Cristovao, Sergipe, Brazil
关键词
Monte Carlo simulation; PET; S value; Internal dosimetry; PERSONAL-COMPUTER SOFTWARE; INTERNAL DOSE ASSESSMENT; POLYGON MESH SURFACES; COMPUTATIONAL PHANTOMS; NUCLEAR-MEDICINE; FEMALE; NEWBORN; ANATOMY;
D O I
10.1016/j.radphyschem.2018.05.011
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
In recent years, positron emission tomography (PET), associated with multi-detector computed tomography (MDCT), has become a diagnostic technique widely disseminated to evaluate various malignant tumors and other diseases. However, during PET/CT examinations, the doses of ionizing radiation experienced by the internal organs of the patients due to F-18 are unknown, and may be substantial. The aim of this study was to determine a set of S values derived from the F-18-FDG and to use them to determine the absorbed and effective doses of 8 different virtual anthropomorphic phantoms (4 of each gender). These phantoms have different Body Mass Index (BMI), to represent different anatomical characteristics of patients examined in PET. The results of the S values were calculated using the MCNPX (2.7.0) Monte Carlo code. These results were compared to the ICRP 106 reference values, obtained with mathematical anthropomorphic phantoms (MIRD model). Our results of the S values were higher than those obtained and presented at the ICRP 106, mainly due to the differences between the phantoms. The differences between the relative distances of the organs and the chemical and physical characteristics of the phantoms used in this study, in relation to mathematical model, reflected the use of a detailed set of phantoms. Therefore, the results presented in this study provide accurate and reliable data for internal dose calculations for patients undergoing PET examinations.
引用
收藏
页码:36 / 41
页数:6
相关论文
共 29 条
  • [1] [Anonymous], 1991, ICRP publication 60, DOI DOI 10.1016/0146-6453(91)90066-P
  • [2] [Anonymous], 2007, ANN, V37
  • [3] Belinato W., 2014, EPJ WEB C INT NUCL P, V66
  • [4] Estimate of S-values for children due to six positron emitting radionuclides used in PET examinations
    Belinato, Walmir
    Santos, William S.
    Perini, Ana P.
    Neves, Lucio P.
    Caldas, Linda V. E.
    Souza, Divanizia N.
    [J]. RADIATION PHYSICS AND CHEMISTRY, 2017, 140 : 51 - 56
  • [5] Blender Foundation, 2017, BLEND FREE OP SOURC
  • [6] MIRD Pamphlet No. 21: A Generalized Schema for Radiopharmaceutical Dosimetry-Standardization of Nomenclature
    Bolch, Wesley E.
    Eckerman, Keith F.
    Sgouros, George
    Thomas, Stephen R.
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2009, 50 (03) : 477 - 484
  • [7] Development of newborn and 1-year-old reference phantoms based on polygon mesh surfaces
    Cassola, V. F.
    Kramer, R.
    de Melo Lima, V. J.
    de Oliveira Lira, C. A. B.
    Khoury, H. J.
    Vieira, J. W.
    Brown, K. Robson
    [J]. JOURNAL OF RADIOLOGICAL PROTECTION, 2013, 33 (03) : 669 - 691
  • [8] Standing adult human phantoms based on 10th, 50th and 90th mass and height percentiles of male and female Caucasian populations
    Cassola, V. F.
    Milian, F. M.
    Kramer, R.
    de Oliveira Lira, C. A. B.
    Khoury, H. J.
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2011, 56 (13) : 3749 - 3772
  • [9] FASH and MASH: female and male adult human phantoms based on polygon mesh surfaces: I. Development of the anatomy
    Cassola, V. F.
    de Melo Lima, V. J.
    Kramer, R.
    Khoury, H. J.
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2010, 55 (01) : 133 - 162
  • [10] Changes in Radiation Dose with Variations in Human Anatomy: Moderately and Severely Obese Adults
    Clark, Landon D.
    Stabin, Michael G.
    Fernald, Michael J.
    Brill, Aaron B.
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2010, 51 (06) : 929 - 932