Chemotherapy in epithelial ovarian cancer

被引:79
作者
Pignata, Sandro [1 ]
Cannella, Lucia [1 ]
Leopardo, Davide [1 ]
Pisano, Carmela [1 ]
Bruni, Giovanni Salvatore [1 ]
Facchini, Gaetano [1 ]
机构
[1] Natl Canc Inst Naples, Dept Urol & Gynecol, Div Med Oncol, I-80131 Naples, Italy
关键词
Ovarian cancer; Chemotherapy; PEGYLATED LIPOSOMAL DOXORUBICIN; PHASE-III TRIAL; PACLITAXEL-RESISTANT OVARIAN; GYNECOLOGIC-ONCOLOGY-GROUP; INTRAPERITONEAL CISPLATIN; INTERGROUP TRIAL; RANDOMIZED-TRIAL; INTRAVENOUS CHEMOTHERAPY; DOCETAXEL-CARBOPLATIN; 1ST-LINE TREATMENT;
D O I
10.1016/j.canlet.2011.01.026
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Epithelial ovarian cancer is the most common type of ovarian cancer; usually occurs in women older than 50 years, and because 75% of cases are diagnosed at stage III or IV it is associated with a poor prognosis. Treatment of ovarian cancer is based on the integration of surgery and chemotherapy. Chemotherapy plays a major role both in the adjuvant treatment and in the care of patients with advanced disease. Several active drugs have been introduced in the treatment of ovarian cancer in the last decades and novel targets and agents are under evaluation. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:73 / 83
页数:11
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