Supramolecular Chemistry in the Biomembrane

被引：37

作者：

Barba-Bon, Andrea ^{[1
]}

Nilam, Mohamed ^{[1
]}

Hennig, Andreas ^{[1
]}

机构：

[1] Jacobs Univ Bremen, Dept Life Sci & Chem, Campus Ring 1, D-28759 Bremen, Germany

来源：

CHEMBIOCHEM | 2020年 / 21卷 / 07期

关键词：

liposomes; membranes; molecular devices; molecular recognition; receptors; ARTIFICIAL SIGNAL-TRANSDUCTION; CONTROLLED MEMBRANE TRANSLOCATION; SYNTHETIC MULTIFUNCTIONAL PORES; CELL-PENETRATING PEPTIDES; RESONANCE ENERGY-TRANSFER; RIGID-ROD MOLECULES; VESICLE FUSION; ION CHANNELS; ANTIMICROBIAL PEPTIDES; ENZYME-ACTIVITY;

D O I：

10.1002/cbic.201900646

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The combination of supramolecular functional systems with biomolecular chemistry has been a fruitful exercise for decades, leading to a greater understanding of biomolecules and to a great variety of applications, for example, in drug delivery and sensing. Within these developments, the phospholipid bilayer membrane, surrounding live cells, with all its functions has also intrigued supramolecular chemists. Herein, recent efforts from the supramolecular chemistry community to mimic natural functions of lipid membranes, such as sensing, molecular recognition, membrane fusion, signal transduction, and gated transport, are reviewed.

引用

页码：886 / 910

页数：25

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