The expression of TCR-γδ/CD3 complex in neoplastic γδ T-cell

被引:0
|
作者
Baseggio, Lucile [1 ]
Berger, Francoise [2 ]
Monneret, Guillaume [4 ]
Magaud, Jean-Pierre [1 ]
Salles, Gilles [3 ]
Felman, Pascale [1 ]
机构
[1] Ctr Hosp Lyon Sud, Lab Hematol Cellulaire, F-69495 Pierre Benite, France
[2] Ctr Hosp Lyon Sud, Serv Anat Pathol, Pierre Benite, France
[3] Ctr Hosp Lyon Sud, Serv Hematol, Pierre Benite, France
[4] Hop Neurol, Lab Immunol, Bron, France
关键词
gamma delta T-cells; HS gamma delta TCL; TCR-gamma delta/CD3 complex; flow cytometry;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We describe that the neoplastic gamma delta T-cells from patients with hepatosplenic gamma delta T-cell lymphoma have a lower expression of TCR-gamma delta/CD3 complex compared to their normal or reactive counterparts. Interestingly, with the use of an appropriate antibody association, this feature is easily and rapidly observed on flow cytometry graphics.
引用
收藏
页码:1717 / 1719
页数:3
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