Dynamics of biopolymers and their hydration water studied by neutron scattering

被引：1
作者：
Chen, S. -H. [1 ]
Chu, X. -Q. [1 ]
Lagi, M. [1 ]
机构：
[1] MIT, Dept Nucl Sci & Engn, Cambridge, MA 02139 USA
来源：
COMPLEX MATERIALS IN PHYSICS AND BIOLOGY | 2012年 / 176卷
关键词：
STRONG LIQUID TRANSITION; PROTEIN DYNAMICS; SUPERCOOLED WATER; SLOW DYNAMICS; CROSSOVER; SOLVENT; FLUCTUATIONS; RELAXATION; MOLECULES; BIOCHEMISTRY;
D O I：
10.3254/978-1-61499-071-0-11
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
In this paper, both the dynamics of a protein and its hydration water are investigated by quasi-elastic neutron scattering (QENS) experiments. In addition, molecular dynamics (MD) simulations of a realistic hydrated protein powder model are also introduced to reproduce the experimental results. We start from the introduction of the incoherent neutron scattering method for studying dynamics of a protein and its hydration water. Then we discuss in details the coupling of the dynamics of a protein and its hydration water, including the following topics: the elastic scan and the reduction from it the mean squared displacement (MSD) of hydrogen atoms in protein and its hydration water; evidence of the dynamic crossover from pressure dependence of the measured relaxation time of hydration water in biopolymers by QENS; synchronization of the dynamic crossover phenomena in other biopolymers and their hydration water; an alternative method for detecting the dynamic crossover temperature. We also show our observation of a logarithmic-like beta-relaxation in the study of intermediate time protein dynamics at the end of this paper.
引用
收藏
页码：11 / 41
页数：31
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