Ethyl-3-(4-fluorophenyl)-6-methyl-4-oxo-2-(1-cyclohexylamino)-3,4-dihydro-furo[2,3-d]pyrimidine-5-carboxylate

被引:5
作者
Sun, Yong [1 ]
Zeng, Guo-Ping [2 ]
Hu, Yang-Gen [3 ,4 ]
机构
[1] Yunyang Teachers Coll, Danjiangkou 442700, Peoples R China
[2] Hubei Univ Educ, Dept Chem & Life Sci, Wuhan 430205, Peoples R China
[3] Cent China Normal Univ, Minist Res, Key Lab Pesticides & Chem Biol, Wuhan 430079, Peoples R China
[4] Yunyang Med Coll, Dept Med Chem, Shiyan 442000, Peoples R China
来源
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2008年 / 64卷
关键词
D O I
10.1107/S1600536807066780
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
In the crystal structure of the title compound, C22H24FN3O4, the two fused rings of furo[2,3-d] pyrimidine form a dihedral angle of 0.88 (13)degrees. The attached benzene ring is twisted with respect to the heterocyclic pyrimidinone ring, making a dihedral angle of 75.07 (12)degrees. The cyclohexyl ring shows a distorted chair conformation. The molecular structure is stabilized by intramolecular C-H center dot center dot center dot O and C-H center dot center dot center dot N hydrogen-bonding interactions. The crystal packing is mainly stabilized by C-H center dot center dot center dot pi hydrogen-bond interactions. Further stability is provided by C-F center dot center dot center dot pi and C-O center dot center dot center dot pi stacking interactions.
引用
收藏
页码:0311 / U5420
页数:13
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