A protein farnesyl transferase involved in abscisic acid signal transduction in Arabidopsis

被引：320

作者：

Cutler, S ^{[1
]}

Ghassemian, M ^{[1
]}

Bonetta, D ^{[1
]}

Cooney, S ^{[1
]}

McCourt, P ^{[1
]}

机构：

[1] UNIV TORONTO, DEPT BOT, TORONTO, ON M5S 3B2, CANADA

来源：

SCIENCE | 1996年 / 273卷 / 5279期

关键词：

D O I：

10.1126/science.273.5279.1239

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The hormone abscisic acid (ABA) modulates a variety of developmental processes and responses to environmental stress in higher plants. A collection of mutations, designated era, in Arabidopsis thaliana that confer an enhanced response to exogenous ABA includes mutations in the Era1 gene, which encodes the beta subunit of a protein farnesyl transferase. In yeast and mammalian systems, farnesyl transferases modify several signal transduction proteins for membrane localization. The era1 mutants suggest that a negative regulator of ABA sensitivity must be acted on by a farnesyl transferase to function.

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页码：1239 / 1241

页数：3

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