Field triage to primary angioplasty combined with emergency department bypass reduces treatment delays and is associated with improved outcome

被引:102
作者
Carstensen, Steen [1 ]
Nelson, Greg C. I.
Hansen, Peter S.
Macken, Lewis
Irons, Stephen
Flynn, Michael
Kovoor, Pramesh
Hoo, Soon Y. Soo
Ward, Michael R.
Rasmussen, Heige H.
机构
[1] Univ Sydney, Royal N Shore Hosp, Dept Cardiol, Sydney, NSW 2006, Australia
[2] Univ Sydney, Royal N Shore Hosp, Dept Emergency, Sydney, NSW 2006, Australia
[3] Ambulance Ser New S Wales, Sydney, NSW, Australia
[4] Univ Sydney, Westmead Hosp, Dept Cardiol, Sydney, NSW 2006, Australia
关键词
myocardial infarction; treatment pathway; primary angioplasty; mortality;
D O I
10.1093/eurheartj/ehm306
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims We investigated the net benefit in the outcome of reducing treatment delay through field triage and emergency department (ED) bypass in patients with ST-elevation myocardial infarction (STEMI) treated with primary angioplasty. Methods and results In a prospective registry study, consecutive patients with suspected STEM] were assigned to: (i) pre-hospital ECG and triage or (ii) ECG and triage at the closest ED, solely based on ambulance availability. Four district hospitals and one regional heart centre serviced the 890 000 population metropolitan area and primary angioplasty was the only reperfusion strategy employed. Baseline characteristics were similar in STEMI patients triaged in the field (108) and the EDs (193). Symptom onset to balloon times: 154 [inter-quartile range (IQR) 120-233) vs. 249 (IQR 184-405) min (P < 0.001) and peak creatine kinase in early presenters (<2 h): 1435 (95 %CI: 904-1966) U/L vs. 2320 (95% CI: 1881-2762) U/L (P = 0.009) were tower in field- than in ED-triaged patients. Mortality in the PCI treated were 1.1 and 8.2% [P = 0.025, RR 0.14 (95% Cl: 0.01-1.08)] and overall mortality were 1.9 and 7.3% [P = 0.046, RR 0.26 (95% CI: 0.05-1.11)]. Conclusion Field-triage and ED bypass were feasible means of reducing treatment delay in patients with suspected STEMI and resulted in smaller infarct size in early presenters and a trend towards a reduction in mortality.
引用
收藏
页码:2313 / 2319
页数:7
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