Therapy of Bronchiectasis

被引：2

作者：

Rademacher, J. ^{[1
]}

Schweigert, M. ^{[2
]}

机构：

[1] Hannover Med Sch, Klin Pneumol, Carl Neuberg Str 1, D-30625 Hannover, Germany

[2] Stadt Klinikum Dresden Friedrichstadt, Klin Allgemein Viszeral & Thoraxchirurg, Dresden, Germany

来源：

ZENTRALBLATT FUR CHIRURGIE | 2015年 / 140卷 / 01期

关键词：

bronchia; bronchiectasis; NCFB; lung disease; CYSTIC FIBROSIS BRONCHIECTASIS; RANDOMIZED CONTROLLED-TRIAL; NON-CF BRONCHIECTASIS; PLACEBO-CONTROLLED TRIAL; SURGICAL-MANAGEMENT; LUNG TRANSPLANTATION; DOUBLE-BLIND; PSEUDOMONAS-AERUGINOSA; DRY POWDER; LONG-TERM;

D O I：

10.1055/s-0033-1358087

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The prevalence of bronchiectasis not due to cystic fibrosis (NCFB) increases with older age. Because of multifaceted etiology of bronchiectasis an extensive diagnostic approach is essential. This includes in-depth anamnesis and a high resolution CT scan of the chest (HRCT). The pathophysiological mechanism with infection, inflammation, secretion retention and destruction determine the therapeutic options. In patients with high rates of exacerbations and severe diseases physicians should think of inhaled antibiotics and macrolids. In case of localized bronchiectasis and failure of conventional therapy surgery of bronchiectasis is an effective treatment option. In some cases surgery is necessary due to haemoptysis, aspergilloma, lung abscess and pleuraempyema. To improve the treatment options of bronchiectasis results of epidemiological, basically and clinical research trials are expected and needed.

引用

页码：113 / 126

页数：14

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